Discrimination between phase-locked and non-phase-locked event-related EEG activity

Kalcher, J.; Pfurtscheller, Gert

doi:10.1016/0013-4694(95)00040-6

Cited by 302 publications

(182 citation statements)

References 10 publications

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“…To analyze the magnitude of TF components, we obtained the TF power for each single response and then averaged across trials. This approach quantifies the total activity (total power) comprising the phase-locked and non-phase-locked fractions of the responserelated activity (for more theoretical explanations, see Kalcher and Pfurtscheller, 1995). For each trial, the time-varying power in a given frequency band was calculated, which was obtained by squaring the absolute value of the convolution of the signal with the complex wavelet.…”

Section: Time-frequency Decompositionmentioning

confidence: 99%

The Role of the BDNF Val66Met Polymorphism for the Synchronization of Error-Specific Neural Networks

Beste¹,

Kolev²,

Yordanova³

et al. 2010

J. Neurosci.

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Behavioral adaptation depends on the recognition of response errors and processing of this error-information. Error processing is a specific cognitive function crucial for behavioral adaptation. Neurophysiologically, these processes are reflected by an event-related potential (ERP), the error negativity (Ne/ERN). Even though synchronization processes are important in information processing, its role and neurobiological foundation in behavioral adaptation are not understood. The brain-derived neurotrophic factor (BDNF) strongly modulates the establishment of neural connectivity that determines neural network dynamics and synchronization properties. Therefore altered synchronization processes may constitute a mechanism via which BDNF affects processes of error-induced behavioral adaptation. We investigate how variants of the BDNF gene regulate EEG-synchronization processes underlying error processing. Subjects (n ϭ 65) were genotyped for the functional BDNF Val66Met polymorphism (rs6265). We show that Val/Val genotype is associated with stronger error-specific phase-locking, compared with Met allele carriers. Posterror behavioral adaptation seems to be strongly dependent on these phase-locking processes and efficacy of EEG-phase-locking-behavioral coupling was genotype dependent. After correct responses, neurophysiological processes were not modulated by the polymorphism, underlining that BDNF becomes especially necessary in situations requiring behavioral adaptation. The results suggest that alterations in neural synchronization processes modulated by the genetic variants of BDNF Val66Met may be the mechanism by which cognitive functions are affected.

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Section: Time-frequency Decompositionmentioning

confidence: 99%

The Role of the BDNF Val66Met Polymorphism for the Synchronization of Error-Specific Neural Networks

Beste¹,

Kolev²,

Yordanova³

et al. 2010

J. Neurosci.

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“…For this analysis, the trial-to-trial variance in oscillatory activity was computed (Kalcher and Pfurtscheller, 1995;Klimesch et al, 1998). This approach effectively removes the contribution of phase-locked activity that is reflected in the average ERP waveform.…”

Section: Analysis Of Stimulus-induced Activitymentioning

confidence: 99%

“…To do this it is helpful to consider the differential contribution of stimulusevoked gamma and beta activity to an average, broad-band ERP waveform (non phase-locked, induced activity is not considered here because it does not contribute to a waveform averaged from multiple single trials: Kalcher and Pfurtscheller, 1995;Klimesch et al, 1998). Figure 7 shows the results of band-pass filtering broad-band auditory-evoked waveforms by two bandpass filters: gamma (30-50 Hz) and beta 1 (12-20 Hz).…”

Section: Comparison With Previous Studies Of Sensory Gatingmentioning

confidence: 99%

“…A final reason for focusing on early, stimulus-locked activity was that we wanted to compare our findings to more standard, ERP-based studies of sensory gating. These studies have employed stimulus-locked timedomain averaged waveforms, which highlight only phase-locked oscillations, whereas nonphase-locked oscillations are averaged out (Kalcher and Pfurtscheller, 1995;Klimesch et al, 1998). Nevertheless, and for the sake of completeness, analysis of stimulus-induced oscillations has been included in the present report, but without specific predictions regarding their relationship to stimulus-driven salience.…”

Section: Introductionmentioning

confidence: 99%

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Gamma and beta neural activity evoked during a sensory gating paradigm: Effects of auditory, somatosensory and cross-modal stimulation

Kisley

Cornwell

2006

Clinical Neurophysiology

116

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Objective.-Stimulus-driven salience is determined involuntarily, and by the physical properties of a stimulus. It has recently been theorized that neural coding of this variable involves oscillatory activity within cortical neuron populations at beta frequencies. This was tested here through experimental manipulation of inter-stimulus interval (ISI).Methods.-Non-invasive neurophysiological measures of event-related gamma (30-50 Hz) and beta (12-20 Hz) activity were estimated from scalp-recorded evoked potentials. Stimuli were presented in a standard "paired-stimulus" sensory gating paradigm, where the S1 (conditioning) stimulus was conceptualized as long-ISI, or "high salience," and the S2 (test) stimulus as short-ISI, or "low salience." Three separate studies were conducted: auditory stimuli only (N=20 participants), somatosensory stimuli only (N=20), and a cross-modal study for which auditory and somatosensory stimuli were mixed (N=40).Results.-Early (20-150 ms) stimulus-evoked beta activity was more sensitive to ISI than temporally-overlapping gamma band activity, and this effect was seen in both auditory and somatosensory studies. In the cross-modal study, beta activity was significantly modulated by the similarity (or dissimilarity) of stimuli separated by a short ISI (0.5 s); a significant cross-modal gating effect was nevertheless detected.Conclusions.-With regard to the early sensory-evoked response recorded from the scalp, the interval between identical stimuli especially modulates beta oscillatory activity.Significance.-This is consistent with developing theories regarding the different roles of temporally-overlapping oscillatory activity within cortical neuron populations at gamma and beta frequencies, particularly the claim that the latter is related to stimulus-driven salience.

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“…This procedure removes the average evoked activity from the data (Kalcher and Pfurtscheller, 1995). The sample point variances were then averaged within consecutive time windows of 125 ms starting at stimulus onset and expressed as percentage change relative to the 375-ms prestimulus baseline, with positive percentages denoting power increases and negative percentages denoting power decreases.…”

Section: Induced Band Powermentioning

confidence: 99%

Changes in brain electrical activity during extended continuous word recognition

et al. 2005

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Twenty healthy subjects (10 men, 10 women) participated in an EEG study with an extended continuous recognition memory task, in which each of 30 words was randomly shown 10 times and subjects were required to make old vs. new decisions. Both event-related brain potentials (ERPs) and induced band power (IBP) were investigated. We hypothesized that repeated presentations affect recollection rather than familiarity.For the 300-to 500-ms time window, an dold/newT ERP effect was found for the first vs. second word presentations. The correct recognition of an doldT word was associated with a more positive waveform than the correct identification of a new word. The old/new effect was most pronounced at and around the midline parietal electrode position. For the 500-to 800-ms time window, a linear repetition effect was found for multiple word repetitions. Correct recognition after an increasing number of repetitions was associated with increasing positivity. The multiple repetitions effect was most pronounced at the midline central (Cz) and fronto-central (FCz) electrode positions and reflects a graded recollection process: the stronger the memory trace grows, the more positive the ERP in the 500-to 800-ms time window. The ERP results support a dual-processing model, with familiarity being discernable from a more graded recollection state that depends on memory strengths.For IBP, we found dold/newT effects for the lower-2 alpha, theta, and delta bands, with higher bandpower during doldT words. The lower-2 alpha dold/newT effect most probably reflects attentional processes, whereas the theta and delta effects reflect encoding and retrieval processes. Upon repeated word presentations, the magnitude of induced delta power in the 375-to 750-ms time window diminished linearly. Correlation analysis suggests that decreased delta power is moderately associated with faster decision speed and higher accuracy. D

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Discrimination between phase-locked and non-phase-locked event-related EEG activity

Cited by 302 publications

References 10 publications

The Role of the BDNF Val66Met Polymorphism for the Synchronization of Error-Specific Neural Networks

The Role of the BDNF Val66Met Polymorphism for the Synchronization of Error-Specific Neural Networks

Gamma and beta neural activity evoked during a sensory gating paradigm: Effects of auditory, somatosensory and cross-modal stimulation

Changes in brain electrical activity during extended continuous word recognition

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