Discrimination of Rhizoma Gastrodiae (Tianma) using 3D synchronous fluorescence spectroscopy coupled with principal component analysis

Fan, Qirui; Chen, Chao-Yin; Huang, Zaiqiang; Zhang, Chunmei; Liang, Pengjuan; Zhao, S. J.

doi:10.1016/j.saa.2014.10.056

Cited by 17 publications

(7 citation statements)

References 16 publications

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“…As a consequence, these plants have been used to produce drugs or health foods which make a great contribution to the increase of economic interest [ 2 ]. However, compared with synthetic medicinal products, their qualities vary drastically on the basis of geographical origin, processing method, growth stage, and so forth [ 3 – 7 ].…”

Section: Introductionmentioning

confidence: 99%

Quantitative and Qualitative Characterization of Gentiana rigescens Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy

Zhang

Zhao

et al. 2017

Journal of Analytical Methods in Chemistry

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Gentiana rigescens Franch (Gentianaceae) is a famous medicinal plant for treatments of rheumatism, convulsion, and jaundice. Comprehensive investigation of different parts and cultivation years of this plant has not yet been conducted. This study presents the quantitative and qualitative characterization of iridoid glycosides from G. rigescens performed by HPLC and FTIR spectroscopy techniques. The accumulations of loganic acid, swertiamarin, gentiopicroside, and sweroside were determined. Results indicated that their content and distribution in different parts and cultivation years exhibit great variations. Gentiopicroside was identified as the most abundant compound among iridoid glycosides and its highest level was observed in the root of 2-year-old plant. With respect to qualitative variation of metabolic profile, the 1800–800 cm−1 band of FTIR spectra successfully discriminated different parts and cultivation years with the aid of PLS-DA. In addition, combined with PLSR, the feasibility of FTIR spectroscopy for determination of gentiopicroside was investigated by selecting characteristic wavelengths (1800–800 cm−1), which presented a good performance with a residual predictive deviation (RPD) of 3.646. Our results suggested that HPLC and FTIR techniques can complement each other and could be simultaneously applied for comparing and analyzing different parts and cultivation years of G. rigescens.

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Section: Introductionmentioning

confidence: 99%

Quantitative and Qualitative Characterization of Gentiana rigescens Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy

Zhang

Zhao

et al. 2017

Journal of Analytical Methods in Chemistry

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“…The technology is used to analyze measured substances quantitatively and qualitatively with the advantages of tracing and highly sensitive, nondestructive, and real-time dynamic detection. Recently, techniques derived from fluorescence spectroscopy (such as fluorescence lifetime imaging [ 4 ], fluorescence in situ hybridization [ 5 ], fluorescence resonance energy transfer [ 6 ], and three-dimensional (3D) fluorescence spectroscopy [ 7 , 8 ]) have been emerged. Since 1990, fluorescence spectroscopy has been widely applied to the assessment of pathophysiology and pharmacodynamics [ 9 ], determination of drug composition and content in vivo [ 10 ], study of drug pharmacological mechanisms [ 11 ], optimization of drug dosage forms, and quality evaluation and identification of TCM ( Fig.…”

Section: Fluorescence Spectroscopy Technologymentioning

confidence: 99%

Development status of novel spectral imaging techniques and application to traditional Chinese medicine

Wang

Zhang

Yang

2023

Journal of Pharmaceutical Analysis

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“…In areas such as Guizhou, Yunnan, Hunan, Sichuan, and Shannxi in China, Rhizoma gastrodiae is used as food in stews, hot pots, and stir-fries by the inhabitants of these regions [ 2 ]. Studies have shown that there are significant differences in chemical composition and pharmacological activity between different origins of Rhizoma gastrodiae [ 3 ]. In Asia, Rhizoma gastrodiae is used both as a food and medicinal plant.…”

Section: Introductionmentioning

confidence: 99%

Differences in Volatile Organic Compounds in Rhizoma gastrodiae (Tian Ma) of Different Origins Determined by HS-GC-IMS

et al. 2023

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Headspace gas chromatography–ion mobility spectrometry (HS-GC-IMS) and principal component analysis (PCA) were used to compare the differences in volatile organic compounds (VOCs) of Rhizoma gastrodiae (Tian Ma) from six different origins in Yunnan, Sichuan, Shaanxi, Anhui, Hubei, and Guizhou. A total of 161 signal peaks were identified, and 84 compounds were characterized, including 23 aldehydes, 19 alcohols, 12 ketones, 8 heterocyclic compounds, 7 esters, 4 phenols, 4 acids, 4 ethers, 2 amines, and 1 alkane. The results of cluster analysis and fingerprint similarity analysis based on principal component analysis and Euclidean distance indicated that there were significant differences between the volatile components of Rhizoma gastrodiae from different origins. This study demonstrated that HS-GC-IMS is simple, rapid, accurate, and has a small sample size and can achieve rapid analysis of the differences in volatile compounds between samples of different origins of Rhizoma gastrodiae.

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Discrimination of Rhizoma Gastrodiae (Tianma) using 3D synchronous fluorescence spectroscopy coupled with principal component analysis

Cited by 17 publications

References 16 publications

Quantitative and Qualitative Characterization of Gentiana rigescens Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy

Quantitative and Qualitative Characterization of Gentiana rigescens Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy

Development status of novel spectral imaging techniques and application to traditional Chinese medicine

Differences in Volatile Organic Compounds in Rhizoma gastrodiae (Tian Ma) of Different Origins Determined by HS-GC-IMS

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