Disease activity, quality of life and indirect costs of psoriatic arthritis in Poland

Kawalec, Paweł; Malinowski, Krzysztof Piotr; Pilc, Andrzej

doi:10.1007/s00296-016-3514-3

Cited by 16 publications

(11 citation statements)

References 13 publications

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“…Chorus et al 24 showed a positive association between work and HRQoL PCS; however, no association was found with MCS. Kawalec et al 25 observed that patients’ HRQoL, expressed as utility scores, was negatively correlated with absenteeism, presenteeism, and indirect costs, suggesting that higher HRQoL was associated with higher productivity and lower indirect costs. Disease-activity score was positively correlated with indirect costs and negatively correlated with HRQoL.…”

Section: Resultsmentioning

confidence: 99%

Patient-reported outcomes in European spondyloarthritis patients: a systematic review of the literature

Torre-Alonso

Queiró

Comellas³

et al. 2018

PPA

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ObjectiveThis review aims to summarize the current literature on patient-reported outcomes (PROs) in spondyloarthritis (SpA).Patients and methodsWe performed a systematic literature review to identify studies (original articles and narrative and systematic reviews) regarding PROs (health-related quality of life [HRQoL], satisfaction, preferences, adherence/compliance, and persistence) in SpA patients published in the European Union through December 2016. International databases (Medline/PubMed, Cochrane Library, ISI Web of Knowledge, Scopus) were searched using keywords in English. The methodological quality of the studies was assessed using the Oxford Centre for Evidence-Based Medicine criteria.ResultsA total of 26 publications met the inclusion criteria. Generally, studies indicated that SpA has a negative impact on patients’ HRQoL. In patients with ankylosing spondylitis, physical domains were more affected than emotional ones, whereas for psoriatic arthritis, both physical and psychological factors were strongly affected by the disease. Data indicated that biological agents (BAs) greatly contributed to improvement in HRQoL in both ankylosing spondylitis and psoriatic arthritis patients. Findings on compliance with BAs were heterogeneous. However, persistence rates exceeded 50% irrespective of the BA administered. Results on preferences indicated that most SpA patients prefer being involved in decisions regarding their treatment and that besides efficacy and safety, frequency and route of administration may influence patients’ preferences for BAs.ConclusionImplementing management programs for SpA patients focuses on the physical, emotional, and social consequences of the disease, in addition to assessing and including patient preferences in the treatment decision-making process, could be crucial to improve patients’ HRQoL and ensure their satisfaction and compliance with treatment.

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Section: Resultsmentioning

confidence: 99%

Patient-reported outcomes in European spondyloarthritis patients: a systematic review of the literature

Torre-Alonso

Queiró

Comellas³

et al. 2018

PPA

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“…The impact of the disease on HRQoL is comparable to other diseases. In arthritis, a number of studies have demonstrated significantly lower quality of life compared to the general population both in patients with rheumatoid arthritis [33][34][35][36][37] and in those with psoriatic arthritis [38][39][40][41] . This underlines the need for new treatment options.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and patient preferences among Danish patients with ulcerative colitis – results from a survey study

Hagelund¹,

Stallknecht²,

Jensen³

2020

Current Medical Research and Opinion

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Objective: To explore health-related quality of life (HRQoL) and assess preferences for medical treatment attributes to obtain information of the relative importance of the different attributes in a Danish population with ulcerative colitis (UC). Methods: We used data from an online survey collected in March 2018 among people with selfreported UC. A total of 302 eligible respondents answered the HRQoL questionnaires (EuroQol-5 Dimensions (EQ-5D-5L) and the Short Inflammatory Bowel Disease Questionnaire (SIBDQ)), and 212 also completed the discrete choice experiment (DCE). The probability of choosing an alternative from a number of choices in the DCE was estimated using a conditional logit model. Results: The respondents had an average SIBDQ score of 4.5 and an HRQoL score of 0.77, applying the EQ-5D-5L questionnaire. HRQoL correlated with disease severity, and the respondents had lower HRQoL than did a gender-and age-matched subset of the Danish population. The most important medical treatment attribute was efficacy within eight weeks. Additionally, respondents stated a preference for avoiding taking steroids, for fast onset of effect and for oral formulations. Conclusions: HRQoL correlates with disease severity, and patients with UC have lower HRQoL than the general population. The most important treatment attribute was efficacy, but patients also would like to avoid steroids, value fast onset of effect and prefer oral formulations. ARTICLE HISTORY

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“…To date, previous studies that have analyzed work absence (absenteeism and short-term disability leave) have typically looked only at patients with psoriasis or PsA, rather than comparing the two [17,18,21,[27][28][29][30]. Fowler et al conducted a matched analysis between patients with and without psoriasis and found that absenteeism accounts for 40% of the economic burden among patients with psoriasis [21].…”

Section: Introductionmentioning

confidence: 99%

Work absenteeism and disability associated with psoriasis and psoriatic arthritis in the USA—a retrospective study of claims data from 2009 TO 2020

Orbai

Reddy

Dennis³

et al. 2021

Clin Rheumatol

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Objectives To compare work absenteeism and short-term disability among adults with psoriasis or psoriatic arthritis (PsA), versus controls in the USA. Methods Adults eligible for work absenteeism and/or short-term disability benefits between 1/1/2009 and 4/30/2020 were screened in the IBM® MarketScan® Commercial and Health and Productivity Management Databases. The following groups were defined: (1) psoriasis: ≥ 2 psoriasis diagnoses ≥ 30 days apart and no PsA diagnoses; (2) PsA: ≥ 2 PsA diagnoses ≥ 30 days apart; (3) control: absence of psoriasis and PsA diagnoses. Controls were matched to psoriasis and PsA patients based on age, gender, index year, and comorbidities. Non-recreational work absences and sick leaves were evaluated in absentee-eligible patients, and short-term disability was evaluated in short-term disability-eligible patients. Costs (in 2019 USD) associated with each type of work absence were evaluated. Results 4261 psoriasis and 616 PsA absentee-eligible and 25,213 psoriasis and 3480 PsA short-term disability-eligible patients were matched to controls. Average non-recreational work absence costs were $1681, $1657, and $1217 for the PsA, psoriasis, and control group, respectively. Compared with psoriasis patients and controls, more PsA patients had sick leaves after 1 year (56.2% versus 55.6% and 41.5%, p < 0.0001). Similarly, short-term disability was more frequent in PsA patients than psoriasis patients and controls at year one (8.8% versus 5.6% and 4.7%, p < 0.0001) and corresponding costs were higher ($605, $406, and $335 on average, p < 0.0001). Conclusion Annual work absenteeism and short-term disability were consistently greater among patients with PsA and psoriasis than controls, highlighting the substantial economic burden of psoriatic disease. Key points• Patients with PsA had greater short-term disability compared with patients with psoriasis and patients with neither psoriasis nor PsA.• Patients with PsA and patients with psoriasis incurred greater non-recreational work absences and sick leaves than patients with neither psoriasis nor PsA.

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Disease activity, quality of life and indirect costs of psoriatic arthritis in Poland

Cited by 16 publications

References 13 publications

Patient-reported outcomes in European spondyloarthritis patients: a systematic review of the literature

Patient-reported outcomes in European spondyloarthritis patients: a systematic review of the literature

Quality of life and patient preferences among Danish patients with ulcerative colitis – results from a survey study

Work absenteeism and disability associated with psoriasis and psoriatic arthritis in the USA—a retrospective study of claims data from 2009 TO 2020

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