Disease burden of COPD in China: a systematic review

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the main contributors to the global burden of disease. The aim of this systematic review was to quantify the disease burden of COPD in China and to determine the risk factors of the disease. The number of studies included in the review was 47 with an average quality assessment score of 7.70 out of 10. Reported COPD prevalence varied between 1.20% and 8.87% in different provinces/cities across China. The prevalence rate of COPD was higher among men (7.76%) than women (4.07%). The disease was more prevalent in rural areas (7.62%) than in urban areas (6.09%). The diagnostic rate of COPD patients in China varied from 23.61% to 30.00%. The percentage of COPD patients receiving outpatient treatment was around 50%, while the admission rate ranged between 8.78% and 35.60%. Tobacco exposure and biomass fuel/solid fuel usage were documented as two important risk factors of COPD. COPD ranked among the top three leading causes of death in China. The direct medical cost of COPD ranged from 72 to 3,565 USD per capita per year, accounting for 33.33% to 118.09% of local average annual income. The most commonly used scales for the assessment of quality of life (QoL) included Saint George Respiratory Questionnaire, Airways Questionnaire 20, SF-36, and their revised versions. The status of QoL was worse among COPD patients than in non-COPD patients, and COPD patients were at higher risks of depression. The COPD burden in China was high in terms of economic burden and QoL. In view of the high smoking rate and considerable concerns related to air pollution and smog in China, countermeasures need to be taken to improve disease prevention and management to reduce disease burdens raised by COPD.

Socioeconomic variations in chronic obstructive pulmonary disease prevalence, diagnosis, and treatment in rural Southwest China

“…Moreover, the prevalence of COPD among the studied population was higher in men than in women, and increased with age. This finding aligns with many previous studies conducted in both high-income and low and middle-income countries [3,4,6,11,12]. The much higher prevalence of COPD in the present study may possibly result from the higher prevalence of current smoking (62.1% among males) in the participant population, as smoking plays a critical role in lung disease development [22].…”

“…In China, COPD ranks among the top three leading causes of death [4]. COPD prevalence has also increased, with the prevalence of COPD among people aged 40 years and over increasing from 2.7% in 1990 to 13.6% in 2015.…”

2019 novel coronavirus (2019-nCoV) outbreak: A new challenge

“…Huang et al and Wang et al [1,12] have shown a rate of chronic obstructive pulmonary disease (COPD) of about 2% and 2,9%, respectively. Subsequently Chen et al [10] have reported a rate of about 1% of respiratory system diseases, different from an estimated COPD prevalence between 1.2-8.9% in different regions of China [16]. Moreover, interstitial lung diseases, history of smoking, bronchiectasis or asthma were underreported [1,[4][5][6][7][8][9][10][11][12][13][14][15].…”

Predictive Value of NLR and Bilirubin Levels in the Readmission of AECOPD

“…Chronic obstructive pulmonary disease(COPD) is a preventable and treatable disease with characteristics of persistent respiratory symptoms and air ow limitation [1]. Because of the ageing population, tobacco exposure and heavy air pollution, the burden of COPD keep growing in China, with high prevalence in Chinese adults [2,3]. According to the Global Burden of Disease Study 2010, COPD were on the top three leading causes of death in China in 2010 [4].…”