2021
DOI: 10.1159/000515304
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Disease Burden, Risk Factors, and Recent Trends of Liver Cancer: A Global Country-Level Analysis

Abstract: <b><i>Background:</i></b> This study aimed to evaluate the updated disease burden, risk factors, and temporal trends of liver cancer based on age, sex, and country. <b><i>Methods:</i></b> We estimated the incidence of liver cancer and its attribution to hepatitis B virus (HBV) and hepatitis C virus (HCV) in 2018 based on the Global Cancer Observatory and World Health Organization (WHO) Cancer Causes database<i>.</i> We extracted the prevalence of risk… Show more

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Cited by 43 publications
(29 citation statements)
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References 34 publications
(38 reference statements)
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“…HCC was diagnosed by pathologic identification or dynamic imaging of abdominal computed tomography (CT) or magnetic resonance imaging (MRI) according to international HCC guidelines. The inclusion criteria were (1)…”
Section: Patientsmentioning
confidence: 99%
See 1 more Smart Citation
“…HCC was diagnosed by pathologic identification or dynamic imaging of abdominal computed tomography (CT) or magnetic resonance imaging (MRI) according to international HCC guidelines. The inclusion criteria were (1)…”
Section: Patientsmentioning
confidence: 99%
“…Hepatocellular carcinoma (HCC) is the most common liver cancer and one of the leading causes of cancer-related deaths worldwide, accounting for approximately 700,000 mortalities per year ( 1 ). HCC at early stage can often be curatively treated by effective options such as surgical resection, liver transplantation, and local ablation, which could lead to better survival outcome ( 2 ).…”
Section: Introductionmentioning
confidence: 99%
“…Over the past decades, liver cancer has been known as one of the primary lethal neoplasms which has a widespread distribution across the globe with a serious threat to the public health [ 33 ]. The present paper provided strong evidence that the patterns of LC [1-MIR] rates and its components were extremely diverse among world super-regions for both genders from 1990 through 2019.…”
Section: Discussionmentioning
confidence: 99%
“…In the past few decades, the incidence of HCC-related deaths has increased. Globally, it is estimated that more than 90,000 new cases of HCC and more than 20,000 deaths related to HCC in 2020 [ 2 ]. The prognosis of hepatocellular carcinoma is poor, with a 3-year survival rate of around 16.6% [ 3 ].…”
Section: Introductionmentioning
confidence: 99%