Disease emergence in multi-host epidemic models

McCormack, Robert K.; Allen, Linda J. S.

doi:10.1093/imammb/dql021

Cited by 34 publications

(34 citation statements)

References 24 publications

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“…According to some ecological mathematics models, the presence of multiple hosts increases the possibility of disease emergence (McCormack & Allen 2007). In this study, JABV was identified for the first time in A. paranaensis.…”

mentioning

confidence: 69%

Detection of the first incidence of Akodon paranaensis naturally infected with the Jabora virus strain (Hantavirus) in Brazil

Oliveira

Guterres

Schrago

et al. 2012

Mem. Inst. Oswaldo Cruz

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We characterised hantaviruses circulating in different Akodon rodent species collected in midwestern Santa Catarina (SC), southern Brazil, where the Jabora hantavirus (JABV) strain was first identified in Akodon montensis. Genetic and phylogenetic analyses based on a partial S segment indicated that, in SC, Akodon paranaensis and A. montensis carried the same type of hantavirus. Additionally, we conducted the first genomic characterisation of the complete S segment from the Brazilian JABV strain. This is the first report of A. paranaensis infected with the JABV

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mentioning

confidence: 69%

Detection of the first incidence of Akodon paranaensis naturally infected with the Jabora virus strain (Hantavirus) in Brazil

Oliveira

Guterres

Schrago

et al. 2012

Mem. Inst. Oswaldo Cruz

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“…The presence of multiple hosts potentially capable of interspecies disease transmission likely influenced, to some extent, the persistence and distribution of these viruses [1], [28], [60], [61]. This is a key area in the ecology and dynamic of an infectious disease and we acknowledged that the presence of numerous hosts should be one of a key area of future model development.…”

Section: Discussionmentioning

confidence: 99%

Rabies and Canine Distemper Virus Epidemics in the Red Fox Population of Northern Italy (2006–2010)

et al. 2013

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Since 2006 the red fox (Vulpes vulpes) population in north-eastern Italy has experienced an epidemic of canine distemper virus (CDV). Additionally, in 2008, after a thirteen-year absence from Italy, fox rabies was re-introduced in the Udine province at the national border with Slovenia. Disease intervention strategies are being developed and implemented to control rabies in this area and minimise risk to human health. Here we present empirical data and the epidemiological picture relating to these epidemics in the period 2006–2010. Of important significance for epidemiological studies of wild animals, basic mathematical models are developed to exploit information collected from the surveillance program on dead and/or living animals in order to assess the incidence of infection. These models are also used to estimate the rate of transmission of both diseases and the rate of vaccination, while correcting for a bias in early collection of CDV samples. We found that the rate of rabies transmission was roughly twice that of CDV, with an estimated effective contact between infected and susceptible fox leading to a new infection occurring once every 3 days for rabies, and once a week for CDV. We also inferred that during the early stage of the CDV epidemic, a bias in the monitoring protocol resulted in a positive sample being almost 10 times more likely to be collected than a negative sample. We estimated the rate of intake of oral vaccine at 0.006 per day, allowing us to estimate that roughly 68% of the foxes would be immunised. This was confirmed by field observations. Finally we discuss the implications for the eco-epidemiological dynamics of both epidemics in relation to control measures.

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“…Spillover events occasionally occur in nature within a geographical region and have been documented for various viruses and sympatric (species occurring in the same geographic region) or syntopic (species sharing the same habitat within the same geographical range) rodent host species, thus providing more evidence that heterologous (secondary) host species are susceptible to infection [9,19,38]. Moreover, multiple host models have indicated that under certain circumstances, persistence of infection within rodent populations can increase with the presence of secondary hosts and spillover [39,40]. Environmental changes that result in greater habitat overlap can create more interspecific encounters that could lead to outbreaks or even the establishment of the viral colonization of a novel host [41].…”

Section: Hantavirus Hostsmentioning

confidence: 99%

Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

Oliveira

Guterres

Fernandes

et al. 2014

Viruses

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Since the recognition of hantavirus as the agent responsible for haemorrhagic fever in Eurasia in the 1970s and, 20 years later, the descovery of hantavirus pulmonary syndrome in the Americas, the genus Hantavirus has been continually described throughout the World in a variety of wild animals. The diversity of wild animals infected with hantaviruses has only recently come into focus as a result of expanded wildlife studies. The known reservoirs are more than 80, belonging to 51 species of rodents, 7 bats (order Chiroptera) and 20 shrews and moles (order Soricomorpha). More than 80genetically related viruses have been classified within Hantavirus genus; 25 recognized as human pathogens responsible for a large spectrum of diseases in the Old and New World. In Brazil, where the diversity of mammals and especially rodents is considered one of the largest in the world, 9 hantavirus genotypes have been identified in 12 rodent species belonging to the genus Akodon, Calomys, Holochilus, Oligoryzomys, Oxymycterus, Necromys and Rattus. Considering the increasing number of animals that have been implicated as reservoirs of different hantaviruses, the understanding of this diversity is important for evaluating the risk of distinct hantavirus species as human pathogens.

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Disease emergence in multi-host epidemic models

Cited by 34 publications

References 24 publications

Detection of the first incidence of Akodon paranaensis naturally infected with the Jabora virus strain (Hantavirus) in Brazil

Detection of the first incidence of Akodon paranaensis naturally infected with the Jabora virus strain (Hantavirus) in Brazil

Rabies and Canine Distemper Virus Epidemics in the Red Fox Population of Northern Italy (2006–2010)

Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

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