Disease patterns of rheumatology outpatients seen in a tertiary hospital serving a multi‐ethnic, urban Asian population in Singapore

Ng, Xinyi; Low, Andrea; Chew, Li‐Ching; Chong, Yong Yeow; Fong, Kok Yong; Lui, Nai Lee; Sim, Eugene; Tan, York Kiat; Yoong, Jon Kah Choun; Thumboo, Julian

doi:10.1111/1756-185x.12016

Cited by 14 publications

(18 citation statements)

References 17 publications

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“…In the present study the most common rheumatic disease was rheumatoid arthritis 60.5%, followed by systemic lupus erythematosus 12.5%, gouty arthritis 8.9% and osteoarthritis 3.3% of patients, similarly Ng et al [7] showed a higher prevalence of rheumatoid arthritis and SLE in a study conducted in Singapore. In contrast to the current study, community-based studies [8] revealed that the osteoarthritis is the most common rheumatic disorder, this can be explained by the relatively young age group in the current study as well as the fact that most cases of osteoarthritis are treated by orthopedic surgeons or general physicians and not usually referred to rheumatic clinics.…”

Section: Discussionsupporting

confidence: 79%

Pattern of Rheumatic Disorders Among Sudanese Patients-Khartoum State

Mirghani¹

2017

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The current study aimed to assess the pattern of rheumatic disorders in Omdurman Teaching Hospital, Khartoum, Sudan. This cross-sectional descriptive study was conducted among Sudanese patients who attended the outpatient rheumatic clinic in Omdurman Teaching Hospital in Sudan during the period from March to September 2013. A structured questionnaire was designed to provide a profile of Sudanese rheumatic patients; the information collected were age, sex, occupation, marital status if receiving follow-up, social status, disabilities and associated chronic diseases. The participants signed a written informed consent, and the Statistical Package for Social Sciences was used for data analysis. Ethical clearance was obtained from the ethical committee of Omdurman Teaching Hospital. The study included a total of 248 subjects; male to female ratio was 1:3. Their ages range from 14-82 years with a mean of 43.6±13.5. The most common disorder was rheumatoid arthritis (60.5%), followed by systemic lupus erythematosus (12.9%), and gouty arthritis (8.9%). Rheumatoid arthritis was most prevalent in female 76.6% versus 23.4%, SLE was found in 87.5% of females as compared to male 12.5%, while gouty arthritis was more common in males 81.8% versus 18.2%. Concerning disability, 36.3% of patients were disabled, 25% of them had left work, and 11.3% had left school. Twenty percent of patients had hypertension, 15.3% had diabetes mellitus, 10% had bronchial asthma, and 5.6% had thyroid disorders. The commonest rheumatic disease was rheumatoid arthritis, followed by SLE and gouty arthritis. Further larger studies are needed to characterize the pattern of rheumatic disorders in this country.

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Section: Discussionsupporting

confidence: 79%

Pattern of Rheumatic Disorders Among Sudanese Patients-Khartoum State

Mirghani¹

2017

IJNPT

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“…Although only limited epidemiological data are available from Asia, prevalence rates are believed to be low (0.02% in China) . In Singapore, PsA patients constituted 4% of outpatients with rheumatologic conditions at a tertiary hospital …”

Section: Introductionmentioning

confidence: 99%

“…1 In Singapore, PsA patients constituted 4% of outpatients with rheumatologic conditions at a tertiary hospital. 2 Disease severity may range from mild to severe and erosive, deforming arthritis. PsA is also associated with metabolic syndrome and a higher risk of cardiovascular death.…”

Section: Introductionmentioning

confidence: 99%

Singapore chapter of rheumatologists' updated consensus statement on the eligibility for government subsidization of biologic and targeted therapy for the treatment of psoriatic arthritis

et al. 2019

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Aim There have been major advances in biologic treatment options for psoriatic arthritis (PsA) since the publication of the 2015 consensus recommendations by the Chapter of Rheumatologists, College of Physicians, Academy of Medicine, Singapore, for government‐assisted funding, thus warranting a revision of this guideline. Methods Recent trials and nine published guidelines on the use of biologic therapy for PsA were reviewed. Based on the synthesized evidence, a task force panel (TFP), consisting of 10 practicing rheumatologists in Singapore, rated the statements pertaining to the use of biologic therapy, using a modified Delphi approach. Consensus was obtained if >70% agreed on a statement. Results The TFP agreed on 10 recommendations pertaining to the initiation, choice and continuation of biologic therapy. A biologic is indicated in patients with PsA: (a) with at least three swollen and tender joints, digits or entheses; and (b) who have failed at least two conventional synthetic disease‐modifying anti‐rheumatic drug (csDMARD) strategies for a minimum of 3 months each. Any approved drug class including tumor necrosis factor inhibitors, interleukin‐17 inhibitors (IL‐17i), IL‐12/23i or targeted synthetic DMARDs may be considered as first‐line treatment, and continued only if a response is achieved by 6 months. Conclusion These recommendations developed through a formal consensus method may be useful to guide funding considerations for appropriate and equitable use of biologic therapy for eligible patients with PsA.

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“…Data from Asia are limited but appear to be similar . Patients with PsA constituted approximately 4% of outpatients with rheumatologic diseases in a cross‐sectional study at a tertiary hospital in Singapore …”

Section: Introductionmentioning

confidence: 99%

“…1 Patients with PsA constituted approximately 4% of outpatients with rheumatologic diseases in a cross-sectional study at a tertiary hospital in Singapore. 2 PsA is heterogeneous, ranging from mild disease to erosive and deforming arthritis, and affects about 30% of individuals with psoriasis. 3 Untreated disease results in progressive joint damage, disability, decreased health-related quality of life (HRQoL) and increased mortality 4 comparable to rheumatoid arthritis (RA).…”

Section: Introductionmentioning

confidence: 99%

Singapore Chapter of Rheumatologists consensus statement on the eligibility for government subsidy of biologic disease modifying anti‐rheumatic agents for the treatment of psoriatic arthritis

et al. 2015

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Disease patterns of rheumatology outpatients seen in a tertiary hospital serving a multi‐ethnic, urban Asian population in Singapore

Abstract: Rheumatoid arthritis, osteoarthritis and crystal arthritis were the three most common rheumatological diseases seen in a tertiary referral centre serving a multi-ethnic urban Asian population in Singapore.

Cited by 14 publications

References 17 publications

Pattern of Rheumatic Disorders Among Sudanese Patients-Khartoum State

Pattern of Rheumatic Disorders Among Sudanese Patients-Khartoum State

Singapore chapter of rheumatologists' updated consensus statement on the eligibility for government subsidization of biologic and targeted therapy for the treatment of psoriatic arthritis

Singapore Chapter of Rheumatologists consensus statement on the eligibility for government subsidy of biologic disease modifying anti‐rheumatic agents for the treatment of psoriatic arthritis

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