Disease severity and quality of life in children with atopic dermatitis: PO-SCORAD in clinical practice

Boccardi, Daniela; D’Auria, Enza; Turati, Federica; Sortino, S.; Riva, Enrica; Cerri, Amilcare

doi:10.23736/s0026-4946.16.04294-8

Cited by 23 publications

(21 citation statements)

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“…When we searched the literature for information about the relationship between comorbid allergic diseases and QoL, it was reported that children with food allergies in addition to AD had lower QoL scores than children who only had AD. 7 Similarly, in our study, it was found that a food allergy was the most common comorbid allergy in the first AD group. However, due to the limited number of patients, we could not conduct any further analyses to investigate the effect of different comorbid allergic diseases on QoL.…”

Section: Discussionsupporting

confidence: 75%

“…[4][5][6] Even though the relationship between AD and QoL is known and the factors that influence the QoL of individuals with AD have been determined, these findings show considerable variation across cultures. [7][8][9][10] To date, QoL studies of AD in different populations have evaluated data, such as the Scoring Atopic Dermatitis (SCORAD) index, ages, and genders, which are factors that are suspected to be associated with AD.…”

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confidence: 99%

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Quality of life of Turkish children and families of Caucasian origin with atopic dermatitis

Ozsaydi

Ercan

Özmen

2021

aei

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Introduction and objectives: To determine the quality of life (QoL) in Caucasian children with atopic dermatitis (AD) and their families and possible factors that might impact their QoL. Materials and methods: In this cross-sectional study, 83 children aged 2–7 with AD and their families were enrolled as the study group, and 83 age-matched healthy children were included as controls. All patients in the AD and control groups were sorted into two age-based groups: (1) 2–4 and (2) 5–7 years of age. The parents of all children completed the Turkish version of the Pediatric Quality of Life Inventory (PedsQL).The Family Impact Scale for Dermatological Diseases (FIS-DD) was administered to the study group. Disease severity was evaluated with the Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) scale. Results: In both age groups, a negative correlation between the PedsQL and the FIS-DD scores (p < 0.001) was found. A positive correlation was found between the PO-SCORAD and FIS- DD scores among the second age group (p = 0.011). In the first age group, AD patients with comorbid allergic diseases had higher FIS-DD scores than those without any other allergic problems (p = 0.007). Conclusions: We suggest that considering family QoL may positively contribute to the treatment of pre-school age AD children.

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Section: Discussionsupporting

confidence: 75%

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confidence: 99%

Quality of life of Turkish children and families of Caucasian origin with atopic dermatitis

Ozsaydi

Ercan

Özmen

2021

aei

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“…42 The intangible burden of AD on the daily lives of patients and their families is extensive and complex Moderate-to-severe AD carries a substantial physical and psychological burden that negatively impacts patients' and families' lives, such as their relationships, social activities, work and emotional wellbeing. 10,11,30,41,44,50,51,52,53,54,55,56,57,58,59 In particular, anxiety, depression, and social isolation are widely experienced in those with AD. 31 Furthermore, a higher risk of suicide ideation, and even attempts, has been reported in patients with AD compared to those without the disease.…”

Section: See Supplementary Materialsmentioning

confidence: 99%

“…Moderate‐to‐severe AD carries a substantial physical and psychological burden that negatively impacts patients' and families' lives, such as their relationships, social activities, work and emotional wellbeing 10,11,30,41,44,50,51,52,53,54,55,56,57,58,59 . In particular, anxiety, depression, and social isolation are widely experienced in those with AD 31 .…”

Section: The Impact or Burden Of Moderate‐to‐severe Ad Is Extensive A...mentioning

confidence: 99%

Unveiling the true costs and societal impacts of moderate‐to‐severe atopic dermatitis in Europe

Augustin

Miséry

Kobyletzki

et al. 2022

Acad Dermatol Venereol

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Atopic dermatitis (AD) is a chronic, auto‐immune condition that imposes a high burden on individuals, society, and the healthcare system. Approximately 4.4% of adults and up to 18.6% of children/adolescents have AD in Europe, with 20% of all cases accounting for moderate‐to‐severe forms. This form of the condition in adults results in annual societal costs across Europe of an estimated €30 billion; €15.2 billion related to missed workdays or reduced work productivity, €10.1 billion related to direct medical costs and €4.7 billion related to personal expenditure of patients/families. AD can also substantially impact physical, emotional, and social quality‐of‐life. Several studies have shown the debilitating itch‐scratch cycle is the main cause of the multifaceted burden, as it causes substantial sleep deprivation and stigmatisation due to the physical appearance of the skin, and confidence issues. These factors lead to psychosocial issues and can cumulate over time and prohibit patients reaching their ‘full life potential’. Despite this, many patients with the condition are undertreated, resulting in uncontrolled symptoms and a further strain placed on patients, society, and the economy. The authors of this White Paper comprise the European Atopic Dermatitis Working Group, which is a network of international specialists with expertise in dermatology and healthcare policy decisions. Their programme of action is focused on harnessing their expertise to build consensus, advance research, share knowledge, and ultimately seek to improve AD care outcomes through achieving long‐term symptom control. This White Paper presents a systematic evaluation of the overall financial and humanistic burden of moderate‐to‐severe AD and the current challenges that exist with AD care. It introduces recommendations for how, collaboratively, key stakeholders and policy makers can support improvements in AD management to achieve better disease control, thus reducing the costs and associated burden placed on individuals, society, and the economy.

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“…AD has a profound impact on the quality of life of the patients and their families because of the burden of its complex signs and symptoms (itch, pain, sleep disturbance...) that affect social functioning and psychological well-being [4][5][6]. For these reasons, patients-reported symptoms and quality of life are also increasingly important in clinical practice [7,8].…”

Section: Introductionmentioning

confidence: 99%

Probiotics, Prebiotics and Postbiotics in Atopic Dermatitis

D’Auria¹,

Pilloni

Beretta

et al. 2019

BJSTR

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Novel strategies are currently under investigation for the prevention and treatment of atopic dermatitis (AD). The supplementation of the diet with probiotics, prebiotics and postbiotics is probably one of the most promising approaches. Hereby, we summarize the current available evidence regarding the use of probiotics, prebiotics and postbiotics in AD. Biotic products seem to have a beneficial effect on AD, especially concerning its prevention. However, the evidence to support the supplementation of the diet with biotics for the management of AD is still not enough to make clear recommendations.

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Disease severity and quality of life in children with atopic dermatitis: PO-SCORAD in clinical practice

Cited by 23 publications

References 0 publications

Quality of life of Turkish children and families of Caucasian origin with atopic dermatitis

Quality of life of Turkish children and families of Caucasian origin with atopic dermatitis

Unveiling the true costs and societal impacts of moderate‐to‐severe atopic dermatitis in Europe

Probiotics, Prebiotics and Postbiotics in Atopic Dermatitis

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