Disease-specific health-related quality of life in patients with esophageal achalasia before and after therapy

Abstract

Disease-specific HRQoL improves in patients with symptomatic achalasia after therapy with dilatation or myotomy. The degree of improvement of HRQoL depends on the degree of improvement of esophageal symptoms.

The adult eosinophilic oesophagitis quality of life questionnaire: a new measure of health-related quality of life

“…Health‐related quality of life is a consistently evaluated patient reported outcome in chronic illness groups 29–34 . Although there has been debate as to whether a disease‐specific or more generalised measure is the superior method to assess HRQOL, 28 current practices involve the use of both assessment types.…”

“…Health-related quality of life is a consistently evaluated patient reported outcome in chronic illness groups. [29][30][31][32][33][34] Although there has been debate as to whether a diseasespecific or more generalised measure is the superior method to assess HRQOL, 28 current practices involve the use of both assessment types. As EoO is a relatively new gastrointestinal diagnosis, a reliable and valid measure of HRQOL specific to the nature of this disease is a critically important step to formulate its treatment paradigms.…”

Patient-Reported Outcomes in Eosinophilic Esophagitis and Achalasia

“…Scores for each domain are calculated as the median of the scores of corresponding items. The responsiveness of the AE-18 instrument was evaluated in 65 prospectively included adult achalasia patients, of whom 47 were dilated and 18 underwent laparoscopic Heller myotomy [44]. Following treatment, AE-18 global score and subscales scores increased; changes in quality of life were associated with improvement in symptoms.…”

Post-Surgical Quality of Life, Psychological State and what Patients Think about the Effectiveness of Heller Myotomy in the Treatment of Achalasia

“…The SF-36 results had a median of 79 points in the No limitation on quality of meals 48 (15) Mild limitation on quality of meals 39 (12) Moderate to severe limitation on quality of meals 13 (4) No limitation on quality of life 29 (9) Presented limitation on quality of life 71 (22) Satisfied with present health 65 (20) Nor satisfied nor disappointed with present health 19 (6) Not satisfied with present health 16 (5) a median (min, max); b percentage (n). physical health domain, and 76 points for the mental health domain.…”