Diseases of the colon and rectum in Bolivia

Rios-Dalenz, Jaime L.; Smith, Lindsay B.; Thompson, Thoburn F.

doi:10.1016/0002-9610(75)90341-4

Cited by 10 publications

(7 citation statements)

References 11 publications

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“…Esophageal disease severity was classified using the criteria established by Ximenes et al., which proposes a four group classification based on the results of the radiological study [11]. The following colonic measurements—defined as normal—wereused to distinguish between normal and abnormal colon findings: rectosigmoid colon of 6.5 cm (width) and 11–35 cm (length), 8 cm (width) and 25 cm (length) for the ascending colon, and 12 cm (width) for the cecum [12, 13, 14, 15, 16].…”

Section: Methodsmentioning

confidence: 99%

Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia

Pinto

Pinazo

Saravia³

et al. 2019

Heliyon

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BackgroundChagas disease (CD) is endemic in Latin America and particularly common in Bolivia, but there is little information on the characteristics of chronic digestive involvement.ObjectivesTo determine the prevalence and characterize digestive manifestations in chronic CD patients in Cochabamba, Bolivia.MethodsEighty-five T. cruzi-seropositive individuals with or without digestive symptoms (G1 group), and fifteen T. cruzi-seronegative patients with similar digestive symptoms to those seen in CD (G2 group) were included in the study. All patients underwent a detailed history including past medical history, epidemiological information, hygiene and dietary habits, a complete physical examination, two serological tests for T. cruzi, video endoscopy, barium swallow, and barium enema.FindingsWe observed digestive manifestations in T. cruzi seropositive and seronegative patients. Colonic manifestations were detected in both groups, highlighting the relevance of other confounder factors in the region. Constipation was present in 52.9% of G1 patients, 62.4% presented two or more upper digestive tract symptoms, and 5.9% of them presented esophageal manifestations. Helicobacter pylori infection was detected in 58.8% of G1 patients, and all patients presented gastritis on endoscopy.ConclusionsPrevalence of digestive involvement in CD patients is higher than expected. However, digestive symptoms are not always caused by T. cruzi infection and require differential diagnoses.

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Section: Methodsmentioning

confidence: 99%

Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia

Pinto

Pinazo

Saravia³

et al. 2019

Heliyon

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“…South America data on diverticulosis prevalence are from quite old studies. In Bolivia, no cases of diverticulosis were described in autopsy records in 1975 [Rios-Dalenz et al 1975]. In Mexico, prevalence of diverticulosis ranged from 4.1% to 9.2% in barium enema studies, while it was 1.9% on necrotic studies [Raña-Garibay et al 2008].…”

Section: Asiamentioning

confidence: 99%

Diverticulosis today: unfashionable and still under-researched

Tursi

2015

Therap Adv Gastroenterol

101

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Diverticulosis of the colon is a widespread disease, and its prevalence is increasing especially in the developing world. The underlying pathological mechanisms that cause the formation of colonic diverticula remain unclear but are likely to be the result of complex interactions among age, diet, genetic factors, colonic motility, and changes in colonic structure. The large majority of patients remain asymptomatic throughout their life, one fifth of them become symptomatic (developing the so-called 'diverticular disease') while only a minority of these will develop acute diverticulitis. The factors predicting the development of symptoms remain to be identified. Again, it is generally recognized that diverticular disease occurrence is probably related to complex interactions among colonic motility, diet, lifestyle, and genetic features. Changes in intestinal microflora due to low-fiber diet and consequent low-grade inflammation are thought to be one of the mechanisms responsible for symptoms occurrence of both diverticular disease and acute diverticulitis. Current therapeutic approaches with rifaximin and mesalazine to treat the symptoms seem to be promising. Antibiotic treatment is currently advised only in acute complicated diverticulitis, and no treatment has currently proven effective in preventing the recurrence of acute diverticulitis. Further studies are required in order to clarify the reasons why diverticulosis occurs and the factors triggering occurrence of symptoms. Moreover, the reasons why rifaximin and mesalazine work in symptomatic diverticular disease but not in acute diverticulitis are yet to be elucidated.

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“…Recent contributions on this topic emphasise colonic diameter as a defining feature [ 9 , 19 , 26 , 27 , 29 – 32 ]. Earlier studies referred to length [ 7 , 30 , 31 , 33 ]. Twelve studies used barium enema or similar studies [ 3 , 7 , 9 , 19 , 27 , 29 , 30 , 32 , 34 , 35 ].…”

Section: Resultsmentioning

confidence: 99%

“…Five studies reported incidence of volvulus, colonic obstruction or faecal impaction with AMC [ 22 , 30 , 31 , 39 , 40 ]. Sigmoid volvulus occurred as follows: Kobak et al (1962) two patients; Rios-Dalenz et al (1975) 49 patients; Ohkubo et al (2014) two patients and Gattuso et al (1997) five patients [ 22 , 30 , 31 , 39 ]. Goulston (1976) described a 6.6:1 rate of impacted faeces, megacolon and volvulus among a psychiatric hospital patients in comparison to a general hospital [ 40 ].…”

Section: Resultsmentioning

confidence: 99%

“…Histologically, evidence supports enteric architectural and neurochemical abnormalities, however, detailed findings are variable [ 23 , 24 , 27 , 30 , 32 , 34 – 39 ]. A proportion of patients with AMC may experience colonic volvulus [ 22 , 30 , 31 , 39 , 40 ]. Furthermore, the condition may have an increased prevalence among patients with neuropsychiatric conditions [ 3 , 28 , 30 , 34 , 35 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

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Symptoms and diagnostic criteria of acquired Megacolon - a systematic literature review

2018

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Background: Acquired Megacolon (AMC) is a condition involving persistent dilatation and lengthening of the colon in the absence of organic disease. Diagnosis depends on subjective radiological, endoscopic or surgical findings in the context of a suggestive clinical presentation. This review sets out to investigate diagnostic criteria of AMC. Methods: The literature was searched using the databases -PubMed, Medline via OvidSP, ClinicalKey, Informit and the Cochrane Library. Primary studies, published in English, with more than three patients were critically appraised based on study design, methodology and sample size. Exclusion criteria were studies with the following features: post-operative; megarectum-predominant; paediatric; organic megacolon; non-human; and failure to exclude organic causes. Results: A review of 23 articles found constipation, abdominal pain, distension and gas distress were predominant symptoms. All ages and both sexes were affected, however, symptoms varied with age. Changes in anorectal manometry, histology and colonic transit are consistently reported. Studies involved varying patient numbers, demographics and data acquisition methods. Conclusions: Outcome data investigating the diagnosis of AMC must be interpreted in light of the limitations of the low-level evidence studies published to date. Proposed diagnostic criteria include: (1) the exclusion of organic disease; (2) a radiological sigmoid diameter of~10 cm; (3) and constipation, distension, abdominal pain and/or gas distress. A proportion of patients with AMC may be currently misdiagnosed as having functional gastrointestinal disorders. Our conclusions are inevitably tentative, but will hopefully stimulate further research on this enigmatic condition.

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Diseases of the colon and rectum in Bolivia

Cited by 10 publications

References 11 publications

Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia

Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia

Diverticulosis today: unfashionable and still under-researched

Symptoms and diagnostic criteria of acquired Megacolon - a systematic literature review

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