Diseases of the gallbladder

Gilger, Mark A.

doi:10.1016/b978-0-7216-3924-6.50070-6

Cited by 3 publications

(7 citation statements)

References 143 publications

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“…Hastalar›n bir k›sm› bulgusuz seyretti¤inden hastal›¤›n gerçek s›kl›¤›n› belirlemek zordur. Yap›lan s›n›rl› say›da çal›flmalarda çocuklardaki s›k-l›¤› %0,13 ile 0,5 aras›nda bildirilmifltir (2,3). Ultrasonografik verilerin geriye dönük de¤erlendirildi¤i bir çal›flmada ise %1,9 gibi daha yüksek oranlarda saptanm›flt›r (4).…”

Section: 9unclassified

“…Hemolitik hastal›klardan baflka, fliflmanl›k, erken do¤um, sepsis, total parenteral beslenme (TPN), kronik karaci¤er hastal›klar›, enflamatuar ba¤›rsak hastal›klar›, k›sa ba¤›rsak sendromu, kistik fibroz ve ilaçlar-dan diüretik ve seftriyakson kullan›mlar› gibi risk etmenleri tan›mlanm›flt›r. Etiolojide en büyük grubu oluflturan hemolitik hastal›klar›n oran› %20'yi geçmezken, ço¤u olguda bir risk etmeni saptanamamaktad›r (2)(3)(4)(5).…”

Section: 9unclassified

“…Çocuklarda da en s›k ergenlik yafl grubunda görüldü¤ü ve k›z cinsiyetin daha üstün oldu¤u bildirilmektedir (7)(8)(9). Pubertede, özellikle kolesterol tafl› s›kl›¤›nda belirgin art›fl görülmesine neden olarak östrojen ve progesteron düzeylerindeki art›fl gösterilmifltir (3,10). Bu hormonlardaki art›fl›n safra staz›n› artt›rd›¤› ve afl›r› kolesterol yap›m›na yol açarak kolesterol iliflkili safra tafl› oluflumuna yol açt›¤› düflünülmektedir (11,12).…”

unclassified

“…Ancak, yap›lm›fl de¤iflik çal›flmalarda olgular›n %23 ile %52 kadar›nda neden saptanamay›p, idiyopatik olarak de¤erlendirilmektedir (3)(4)(5)(6)(7)13). Bizim çal›flmam›zda da hastalar›n 26's›nda (%43) herhangi bir risk etmeni saptanamam›flt›r.…”

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Çocukluk çağında safra taşları: 60 olgunun geriye dönük incelenmesi

Fakirullahoğlu¹,

Dinler²,

Kalaycı³

2011

tpa

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Ç Ço oc cu uk kl lu uk k ç ça a¤ ¤› ›n nd da a s sa af fr ra a t ta afl fll la ar r› ›: : 6 60 0 o ol lg gu un nu un n g ge er ri iy ye e d dö ön nü ük k i in nc ce el le en nm me es si i G Ga al ll ls st to on ne es s i in n c ch hi il ld dh ho oo od d: : R Re et tr ro os sp pe ec ct ti iv ve e a an na al ly ys si is s o of f 6 60 0 c ca as se es s F Fa at ti ih h F Fa ak ki ir ru ul ll la ah ho o¤ ¤l lu u, , G Gö ön nü ül l D Di in nl le er r* *, , A Ay yh ha an n G Ga az zi i K Ka al la ay yc c› ›* * S Su um mm ma ar ry yAim: The purpose of this study was to documentation of the characteristics of children with cholelithiasis by means of age, sex, clinical manifestations and risk factors. Material and Method: Sixty cases (aged 0-18 years) with ultrasonographic evidence of cholelithiasis were enrolled in the study. Results: Mean age of the patients was 7.8±5.1 years (range: 0.25-18 years), 38 (63.3%) of them were females. Underlying risk factors were identified in 34 (56.7%) of cases (15 ceftriaxone use, six hemolytic diseases, five Down's syndrome, four obesity, two total parenteral nutrition and sepsis, one inflammatory disease and one chronic cholestatic liver disease). No etiology could be found in 26 (43.3%) patients who were defined as idiopathic. Of 46 patients who were followed at least for three months, eight (17.4%) had cholecystectomy, 16 (34.8%) showed differences in stone size and the stones were resolved in 24 patients (52.2%). When the cases related to ceftriaxone use were excluded, the percentage of the disappaerance of the stones was found to be 28.3%. Ursodeoxycolic acid was effective on resolution of symptoms in 69.2% of patients. The complications of gallstones were recorded in five (8.3%) patients. Conclusions: Cholelithiasis is more common in children than previously thought. The most common risk factors are ceftriaxone use and hemolytic diseases but about half of the cases are still idiopathic. There is a need for close monitoring of patients in especially risk groups because of gallstone development and its complications. (Turk Arch Ped 2010; 45: 119-23)

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Section: 9unclassified

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Çocukluk çağında safra taşları: 60 olgunun geriye dönük incelenmesi

Fakirullahoğlu¹,

Dinler²,

Kalaycı³

2011

tpa

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“…Normal gallbladder motility is crucial in preventing the formation of gallstone (15). A decrease in gallbladder motility with insufficient emptying may produce crystallization of the gallbladder bile (16,17). It has been experimentally demonstrated that impaired gallbladder motility is the most important factor in gallstone formation (18).…”

mentioning

confidence: 99%

Gallbladder Motility in Children With Down Syndrome

Taşdemir,

Çetinkaya,

Polat

et al. 2004

J. pediatr. gastroenterol. nutr.

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Objective:The aim of this study was to investigate gallbladder motility in children with Down syndrome by measuring gall‐bladder volume and contraction index.Methods:This study, performed between January 2001 and December 2002 at the Ondokuz Mayis University, School of Medicine, Department of Paediatric Neurology, Samsun, Turkey, included 21 patients with Down syndrome (study group) and 22 healthy children (control group). After an 8‐hour fast, gallbladder diameters in both groups were measured in length, width, and height by ultrasonography before and 30 minutes after a test meal. The volume of gallbladder before and after a test meal was determined, and the contraction index was calculated. Blood triglyceride and cholesterol levels were measured, and 5‐hydroxyindoleacetic acid (5‐HIAA) levels in urine were determined.Results:Mean gallbladder volume before test meal in the study group and controls was 8,412.4 ± 5,174 mm3 and 16,516.8 ± 6,796.1 mm3 (P < 0.001), respectively. The mean contraction index of the study group was 41.2% ± 19.4% and of controls, 75.0% ± 12.3% (P < 0.001). The mean triglyceride level of the study group was significantly higher than controls (P < 0.05). The mean urine 5‐HIAA level of the study group was lower than controls (P < 0.05).Conclusion:CI was lower in patients with Down syndrome, suggesting gallbladder hypomotility. Hypomotility may be a feature associated with the high prevalence of gallstones in Down syndrome.

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Vomiting in the Pediatric Age Group

Mullen

2009

Pediatric Health

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Vomiting is a common complaint in any healthcare facility that deals with children. A child recently presented to our emergency department with an occult cause of vomiting, which led to the development of the following differential diagnosis of vomiting in children. Although usually of gastrointestinal origin, vomiting can be caused by the dysfunction of many different organ systems, the results of which may range from benign to life threatening. The differential diagnosis is presented in order of frequency, in order to make it as clinically relevant as possible, and then each section is further broken down to the pathophysiology, the historical facts, the pertinent physical examination findings, and the therapeutics of each diagnosis is discussed in variable detail.

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Diseases of the gallbladder

Cited by 3 publications

References 143 publications

Çocukluk çağında safra taşları: 60 olgunun geriye dönük incelenmesi

Çocukluk çağında safra taşları: 60 olgunun geriye dönük incelenmesi

Gallbladder Motility in Children With Down Syndrome

Vomiting in the Pediatric Age Group

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