Diseases of the Peritoneum

Clement, Philip B.

doi:10.1007/978-1-4757-3889-6_17

Cited by 69 publications

(56 citation statements)

References 405 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intrinsic ureteral endometriosis is histologically defined when DIE lesions infiltrate the muscularis of the ureteral wall. Ureteral endometriosis is considered as extrinsic when DIE lesions are responsible for a significant ureteral obstruction but without involvement of the ureteral muscularis (3).…”

mentioning

confidence: 99%

Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions

Chapron

Chiodo

Leconte

et al. 2010

Fertility and Sterility

View full text Add to dashboard Cite

mentioning

confidence: 99%

Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions

Chapron

Chiodo

Leconte

et al. 2010

Fertility and Sterility

View full text Add to dashboard Cite

“…However, endometriosis shares many clinicopathologic characteristics with epithelial ovarian neoplasms, including ovarian carcinomas [2]. Malignant transformation of endometriosis, though never very common, has repeatedly been documented since Sampson's time [1,3,4]. In general, a neoplasm's characteristics are determined by several events in its biological background: abnormal cellular proliferation, DNA alterations, abnormal neovascularization, monoclonality, and so on.…”

Section: Introductionmentioning

confidence: 99%

“…Clinically, endometriosis is essentially benign, and it only rarely develops malignant changes [1]. However, endometriosis shares many clinicopathologic characteristics with epithelial ovarian neoplasms, including ovarian carcinomas [2].…”

Section: Introductionmentioning

confidence: 99%

Proliferative Activity and Genetic Alterations in <i>TP53</i> in Endometriosis

Toki¹,

Nakayama²

2000

Gynecol Obstet Invest

View full text Add to dashboard Cite

In the secretory phase of the menstrual cycle, proliferative activity and expression levels of cell cycle-regulatory molecules are higher in endometriotic lesions than in the corresponding eutopic endometrium. In some endometriotic lesions, proliferative activity remains high in the postmenopausal period. By immunostaining, one can recognize TP53 overexpression in epithelial cells in a considerable number of endometriotic lesions. In those endometriotic lesions that show TP53 overexpression, neither TP53 point mutations (exons 5 to 8) nor microsatellite alterations (microsatellite instability or loss of heterozygosity) has been detected. Thus, the TP53 overexpression demonstrated in endometriotic epithelia seems to result from an overproduction of wild-type TP53 protein. The biological role of TP53 in endometriotic lesions is still unclear.

show abstract

“…Presence of malignant cells in ascites and widespread peritoneal tumor with superficial invasion of pelvic organs are the typical intrao perative appearance of PSPC [5,6], Neither these charac teristics nor immunoperoxidase staining of DPAS or PAS were positive in this case, excluding PSPC from the diag nosis [7], Besides, tumor cells in this case were different from the mésothélial cells by being bland and uniform and by containing microvilli and vesicular nuclei. They did not have microcystic or sarcomartoid microscopic patterns, which are characteristic of malignant mesothe lioma [6], The diagnosis of the peritoneal metastasis was the most likely. In fact, metastatic neoplasms are by far the most common tumors encountered in the female peri toneum [5], Most are associated with known primary tumor sites, such as the ovary, the gastrointestinal tract, or the breast.…”

Section: Discussionmentioning

confidence: 91%

Successful Management of a Solitary Peritoneal Metastasis of Unknown Origin

Wang

Yuan²,

Chao³

et al. 1997

Gynecol Obstet Invest

View full text Add to dashboard Cite

A solitary peritoneal metastasis from a poorly differentiated adenocarcinoma of unknown origin in a 38-year-old female is described. The patient presented with a left ovarian tumor and elevated cancer antigen 125. She underwent complete excision of tumor and received six courses of postoperatively adjuvant cisplatin-based combination plus radiation therapy simultaneously. Second-look operation was done later and complete surgicopathologic remission was demonstrated. Two further courses of consolidation chemotherapy were given. She has been followed up for 25 months, and is living and well. We suggest that the combination of aggressive surgery, cisplatin-based chemotherapy and an open-field technique of abdominopelvic irradiation (concurrent chemoradiation) may be an appropriate approach to manage solitary peritoneal metastases from poorly differentiated adenocarcinoma of unknown origin.

show abstract

Diseases of the Peritoneum

Cited by 69 publications

References 405 publications

Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions

Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions

Proliferative Activity and Genetic Alterations in <i>TP53</i> in Endometriosis

Successful Management of a Solitary Peritoneal Metastasis of Unknown Origin

Contact Info

Product

Resources

About