Post COVID-19 syndrome, according to the WHO, is a disease that occurs in individuals with a history of SARS-CoV-2 infection, usually within three months from its onset. It is characterized by persistent clinical manifestations related to the sensory organs. The objective of this review is to determine the Post COVID-19 symptoms in the orofacial region in Latin America with emphasis on the Andean region. A literature review was conducted based on publications from 2020 to 2022, using several digital databases, including PubMed, Latindex, and Google Scholar. After applying an inclusion and exclusion criteria, 24 articles were selected for the analysis of Post COVID-19 symptoms in the Andean region. The most common manifestations reported were fatigue, myalgia, and headaches. In regards to the orofacial region, the main symptoms included dysgeusia, anosmia, and to a lesser extent, tinnitus, and xerostomia. The symptoms with the highest prevalence withing the Post COVID-19 syndrome were dysgeusia, hypogeusia, and ageusia as well as anosmia, which were among the most frequent in the orofacial region. Visual disturbances such as red eye and vision loss were also reported, as well as minor alterations of the oral mucosa. These conditions are important and have persistent symptoms, requiring further studies on the subject. A thorough medical history is recommended to identify specific symptoms and signs in Post COVID-19 patients.