2008
DOI: 10.1590/s0102-76382008000200015
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Disfunção cognitiva após cirurgia cardíaca

Abstract: Postoperative cognitive dysfunction, frequent in cardiac surgeries, leads to major consequences. The physiopathological processes involved in this condition are still not completely elucidated, though its multifactor character is known. Besides pre-operative factors such as age and education, some intra-operative factors are of extreme importance. However, according to a vast literature on the subject, these factors are not sufficient to totality clarify the etiology of all cases, thus suggesting a genetic bas… Show more

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Cited by 18 publications
(8 citation statements)
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“…A literature review discussed the main factors involved in neurological injury following cardiac surgery and assessed the pharmacotherapy used to prevent it (28). This study indicates that ECC and perfusion time is an intraoperative risk factor associated with the duration of the procedure.…”
Section: Discussionmentioning
confidence: 91%
“…A literature review discussed the main factors involved in neurological injury following cardiac surgery and assessed the pharmacotherapy used to prevent it (28). This study indicates that ECC and perfusion time is an intraoperative risk factor associated with the duration of the procedure.…”
Section: Discussionmentioning
confidence: 91%
“…Of the risk factors involved in neurocognitive dysfunction in the perioperative period, three specifically stand out: age, educational level, and previous diseases. Particularly important risk factors in the intraoperative period are as follows: embolus formation; CPB time; air bubbles originating from the oxygenator; blood pressure level; and the temperature elevation that may occur in the postoperative period 16 , 17 .…”
Section: Discussionmentioning
confidence: 99%
“…This evolution of new knowledge minimized the deleterious effects of CPB and with the addition of accessories such as arterial filters and bubble detectors; it has reduced the morbimortality in cardiac surgery procedures with CPB [38,[43][44][45]. However, the incidence, still frequent of neurological complications remains a challenge because, despite all the advances, neurologic complications still occur and are causes of serious damage [4].…”
Section: Discussionmentioning
confidence: 99%