Disinhibition syndromes, secondary mania and bipolar disorder in old age

Shulman, Kenneth I.

doi:10.1016/s0165-0327(97)00156-0

Cited by 71 publications

(35 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Significant right hemisphere activation during response inhibition is shown on one subject's anatomy. Areas shown include the inferior frontal gyrus (1), middle frontal gyrus (2), insula (3), and inferior parietal lobule (4). The axial slice is 41 mm anterior to the anterior commissure, and the anatomy has been made slightly transparent to reveal the activation that lies just below the cortical surface.…”

Section: Figmentioning

confidence: 99%

“…Response-inhibition deficits have been implicated in such clinical syndromes as attention deficit hyperactivity disorder (1), Tourette's syndrome (2), obsessive-compulsive disorders (3), and assorted ''disinhibition syndromes'' (4). The ability to selectively attend to a subset of a complex environment, activate appropriate meanings during verbal and written language comprehension, and activate appropriate memories at encoding and retrieval may all be critically dependent on the ability to suppress interfering stimuli, interpretations, and memories, respectively (5).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Right hemispheric dominance of inhibitory control: An event-related functional MRI study

Garavan

Ross

Stein

1999

Proc. Natl. Acad. Sci. U.S.A.

1,284

137

966

View full text Add to dashboard Cite

Normal human behavior and cognition are reliant on a person's ability to inhibit inappropriate thoughts, impulses, and actions. The temporal and spatial advantages of event-related functional MRI (fMRI) were exploited to identify cortical regions that showed a transient change in fMRI signal after the withholding of a prepotent motor response. The temporal specificity of the event-related fMRI design also minimized possible contamination from response inhibition errors (i. e., commission errors) and other extraneous processes. Regions identified were strongly lateralized to the right hemisphere and included the middle and inferior frontal gyri, frontal limbic area, anterior insula, and inferior parietal lobe. Contrary to the prominence traditionally given to ventral frontal regions for response inhibition, the results suggest that response inhibition is accomplished by a distributed cortical network.

show abstract

Section: Figmentioning

confidence: 99%

mentioning

confidence: 99%

Right hemispheric dominance of inhibitory control: An event-related functional MRI study

Garavan

Ross

Stein

1999

Proc. Natl. Acad. Sci. U.S.A.

1,284

137

966

View full text Add to dashboard Cite

show abstract

“…16 The brain regions which have been implicated in secondary mania after HSV encephalitis are also the same. 10 Starkstein et al proposed that lesions involving basal ganglia and thalamus produce a bipolar type of mood disorde whereas lesions of the cortex produce manic syndrome that is not followed by a cyclic mood disorder.…”

Section: Discussionmentioning

confidence: 99%

Mood Disorder due to Herpes Simplex Encephalitis with Neuroimaging Findings Limited to the Right Hemisphere and Cerebellum: Case Report

Topçuoğlu¹,

Gönentür²,

Topçuoğlu³

et al. 2012

Turkiye Klinikleri J Med Sci

View full text Add to dashboard Cite

A AB BS ST TR RA AC CT T Herpes simplex (HSV) encephalitis may cause psychiatric syndromes including mood disorder episodes. A case of secondary mood disorder after HSV encephalitis is reported in this paper. The aim of this case presentation is to discuss the neuroanatomic regions of the brain associated with secondary mood disorders in the light of the patient's neuroimaging findings. A 62-year-old patient with HSV encephalitis developed a depressive episode for the first time followed by a manic episode. The patient's magnetic resonance imaging scan showed cerebral atrophy mainly affecting the right temporal lobe and cerebellar atrophy as well as perfusion defects in the right amygdala, right basal ganglion and right temporal cortex as seen in the single-photon emission computed tomography (SPECT). The findings were consistent with defects located exclusively in the right cerebral hemisphere. To the best of our knowledge, the cerebellar pathology has been demonstrated for the first time in a mood disorder case secondary to HSV. Neuroimaging findings of the secondary mood disorder cases may contribute to a better understanding of the neuroanatomical regions of this, yet not fully understood mood disorder.K Ke ey y W Wo or rd ds s: : Encephalitis, herpes simplex; bipolar disorder; aged Ö ÖZ ZE ET T Herpes simpleks (HSV) ensefaliti duygudurum epizodlarını da içeren psikiyatrik sendromlara neden olabilir. Bu yazıda HSV ensefalitinden sonra gelişen bir sekonder duygudurum bozukluğu olgusu bildirilmektedir. Bu olgu sunumunun amacı, beynin sekonder duygudurum bozukluğu ile ilişkili olabilecek nöroanatomik bölgelerini, hastanın nörolojik görüntüleme bulguları ışığında tartışmaktır. Altmış iki yaşındaki bir hastada, HSV ensefalitinin ardından önce bir depresif epizod ve daha sonra bir manik epizod gelişmiştir. Hastanın manyetik rezonans görüntülemesinde özellikle sağ temporal lobda olmak üzere serebral ve serebellar atrofi ve tek foton emisyon bilgisayarlı tomografide (SPECT) sağ amigdalada, sağ bazal ganglion ve sağ temporal kortekste perfüzyon defektleri izlendi. Görüntüleme bulguları sağ serebral hemisfer ile sınırlıydı. Bildiğimiz kadarıyla bir HSV ensefaliti sonrası gelişen duygudurum bozukluğu olgusunda serebellar patoloji ilk kez göste-rilmiş olmaktadır. Sekonder duygudurum bozukluğu olgularının beyin görüntüleme bulguları bu bozuklukla ilişkili nöroanatomik bölgelerin anlaşılmasına katkıda bulunacaktır.A An na ah ht ta ar r K Ke el li im me el le er r: : Ensefalit, herpes simpleks; bipolar bozukluk; yaşlı T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J M Me ed d S Sc ci i 2 20 01 12 2; ;3 32 2( (6 6)

show abstract

“…Nöroloji kliniğindeki izleminde trombosit sayısı 919.000x10 9 /L olan olgunun inme sonrasındaki altı yıllık süreçte duygudurum veya psikotik bozukluğu düşündürecek herhangi bir psikiyatrik yakınması olmadığı, değişken süreler ve dozlarda salisilat, heparin ve anagrelid tedavisi aldığı bilinmekte idi. Epikriz notlarından, söz konusu serebrovasküler olayın ET ile ilişkilendirildiği rapor edilmişti.…”

Section: Olgu Sunumuunclassified

“…2,3 Tam kan sayımında 600.000x10 9 /L üzerinde trombosit sayısı ile tanı konulmaktadır. 1 Trombositoza yol açan ikincil nedenlerin dışlanması ET tanısı koymak için elzemdir.…”

unclassified

Late Onset Manic Episode Following a Stroke Related Essential Thrombocytosis: Case Report

Balcıoğlu¹,

Türe²,

Eradamlar³

2016

Turkiye Klinikleri J Neur

View full text Add to dashboard Cite

Disinhibition syndromes, secondary mania and bipolar disorder in old age

Cited by 71 publications

References 50 publications

Right hemispheric dominance of inhibitory control: An event-related functional MRI study

Right hemispheric dominance of inhibitory control: An event-related functional MRI study

Mood Disorder due to Herpes Simplex Encephalitis with Neuroimaging Findings Limited to the Right Hemisphere and Cerebellum: Case Report

Late Onset Manic Episode Following a Stroke Related Essential Thrombocytosis: Case Report

Contact Info

Product

Resources

About