Disparity between angiographic coronary lesion complexity and lipid core plaques assessed by near‐infrared spectroscopy

Abstract

Angiographic SYNTAX score only weakly correlated with LCBI. It is of interest as well that high LCBI was also present in cases of low SYNTAX scores. The disparity between the degree of angiographic complexity and the amount of LCP supports postulated mechanisms of the adverse event propensity even in patients who demonstrate low angiographic complexity. Future studies are necessary to address the clinical significance of high LCBI in patients with low-to-intermediate angiographic complexity and their potential for PCI-related complications.

Intracoronary Near-Infrared Spectroscopy (NIRS) Imaging for Detection of Lipid Content of Coronary Plaques: Current Experience and Future Perspectives

“…et .al [31]201320To describe NIRS findings of culprit lesions in STEMIPlaques causing STEMI have a high LCBI JACC Cardiovasc Interv Zynda, T.K. et .al [32]201378To determine if there was a relationship between angiographic lesion complexity and the extent of LCP identified by catheter-based NIRSAngiographic SYNTAX score weakly correlated with lipid core burden index Catheter Cardiovasc Interv Choi, B.J. et .al [33]201332To investigate whether coronary endothelial dysfunction is associated with the LCP in patients with early CADPatients with early CAD and endothelial dysfunction had a higher lipid content in the vascular wall than patients with normal endothelial function; Eur Heart J

ACS acute coronary syndrome; CAD coronary artery disease; IVUS intravascular ultrasound; LAD left artery descending; LCBI lipid core burden index; LCP lipid core-containing plaque; LCX left circumflex artery; MI myocardial infarction; NIRS near-infrared spectroscopy; PCI percutaneous coronary intervention; QCA Quantitative Coronary Angiography; RCA right coronary artery; STEMI ST-segment elevation myocardial infarction; *number of patients

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