Dispersion and functionalization of single-walled carbon nanotubes (SWCNTS) for nanocomposite applications

Yaya, Abu; Gebremariam, Abraham Teklay; Annan, Ebenezer; Efavi, Johnson Kwame; Tiburu, Elvis K.; Onwona-Agyeman, B.; Jensen, Lars Rosgaard

doi:10.1051/mattech/2017009

Cited by 3 publications

(3 citation statements)

References 38 publications

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“…SWNTs (Type1-73,953) of minimum 90% assay with diameter 1-2 nm and about 5-30 μm long was purchased from SRL India. In this work, non-covalent type of functionalization was adopted as opposed to covalent type of functionalization [25][26][27][28] because it disperses the SWNTs quite effectively without affecting the structural and electrical properties of the SWNTs 29,30 . About 0.25 mg/ml of SWNTs were mixed in 100 mg aqueous solution of sodium dodecylbenzenesulfonate (SDBS) surfactant.…”

Section: Methodsmentioning

confidence: 99%

Acid-modified CNT/Zinc Oxide nanowires based high performance broadband photodetector

Aier

Dhar

2023

Sci Rep

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In this study, the authors have reported the impact of post-treatment via exposure to acid on single walled carbon nanotubes (SWNTs) thin film (TF) based SWNT/ZnO Nanowire (NW) broad band photodetector. The ZnO NWs were deposited on SWNT (with and without acid-treated) using a simple catalytic free process called glancing angle deposition (GLAD) technique. Acid-treated SWNT samples warranted the growth of high quality ZnO NWs over them. On fabricating photodetectors with the acid-treated ZnO NW/SWNT TF heterostructure (HS) gave better device performance as compared to the as-deposited ZnO NW/SWNT TF HS (without acid-treatment) sample. The acid-treated device showed a large responsivity (85.45 A/W), specific detectivity (0.859 × 1012 Jones) and with a low noise equivalent power of 3.9101 pW values. Moreover, the oxygen adsorption–desorption mechanism in SWNTs impacted the electrical resistance of the nanotubes which affected nanotube conductivity. The acid-treatment favoured relatively faster charge separation at the ZnO NW/SWNT heterojunction thus providing a fast device response (trise = 0.11 s, tfall = 0.39 s at + 5 V). The fabricated acid-treated device showed good broad band detection (250 nm-750 nm) which was explained with respect to the optical absorption profile of the sample.

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Section: Methodsmentioning

confidence: 99%

Acid-modified CNT/Zinc Oxide nanowires based high performance broadband photodetector

Aier

Dhar

2023

Sci Rep

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“…To achieve a high degree of SWCNT dispersion, two approaches are commonly used: opening the end caps of the tubes or attaching functional groups to their side walls. The cutting of SWCNTs has been carried out by the use of concentrated acids, fluorination, or ultrasonication [54].…”

Section: Introductionmentioning

confidence: 99%

Poly(vinyl chloride)/Nanocarbon Composites for Advanced Potentiometric Membrane Sensor Design

Zhizhin,

Turyshev,

Shpigun

et al. 2024

IJMS

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Polymer nanocomposites filled with carbon nanoparticles (CNPs) are a hot topic in materials science. This article discusses the current research on the use of these materials as interfacial electron transfer films for solid contact potentiometric membrane sensors (SC-PMSs). The results of a comparative study of plasticized poly (vinyl chloride) (pPVC) matrices modified with single-walled carbon nanotubes (SWCNTs), fullerenes-C60, and their hybrid ensemble (SWCNTs-C60) are reported. The morphological characteristics and electrical conductivity of the prepared nanostructured composite films are reported. It was found that the specific electrical conductivity of the pPVC/SWCNTs-C60 polymer film was higher than that of pPVC filled with individual nanocomponents. The effectiveness of this composite material as an electron transfer film in a new potentiometric membrane sensor for detecting phenylpyruvic acid (in anionic form) was demonstrated. Screening for this metabolic product of phenylalanine in body fluids is of significant diagnostic interest in phenylketonuria (dementia), viral hepatitis, and alcoholism. The developed sensor showed a stable and fast Nernstian response for phenylpyruvate ions in aqueous solutions over the wide linear concentration range of 5 × 10−7–1 × 10−3 M, with a detection limit of 10−7.2 M.

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“…Multiple functionalization strategies for MWCNTs have been described in the literature [ 12 , 16 ]. Functionalization of MWCNTs to increase solvent dispersibility and provide anchoring groups for covalently linking ligands for targeted drug delivery typically requires hazardous chemicals and expensive reagents such as chitosan, polyethylene glycol, ethylene diamine, peptides, vitamins, and antibodies [ 17 – 19 ]. MWCNTs are often functionalized by introducing carboxyl groups, amino groups, or hydroxyl groups on its surface, which are then conjugated to a targeting ligand via a linker or through direct conjugation.…”

Section: Introductionmentioning

confidence: 99%

In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin

Thakur,

Martins,

Karthikeyan

et al. 2024

J Mol Model

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Context Multiwalled carbon nanotubes (MWCNTs) functionalized with lysine via 1,3-dipolar cycloaddition and conjugated to galactose or mannose are potential nanocarriers that can effectively bind to the lectin receptor in MDA-MB-231 or MCF-7 breast cancer cells. In this work, a method based on molecular dynamics (MD) simulation was used to predict the interaction of these functionalized MWCNTs with doxorubicin and obtain structural evidence that allows a better understanding of the drug loading and release process. The MD simulations showed that while doxorubicin only interacted with pristine MWCNTs through π-π stacking interactions, functionalized MWCNTs were also able to establish hydrogen bonds, suggesting that the functionalized groups improve doxorubicin loading. Moreover, the elevated adsorption levels observed for functionalized nanotubes further support this enhancement in loading efficiency. MD simulations also shed light on the intratumoral pH-specific release of doxorubicin from functionalized MWCNTs, which is induced by protonation of the daunosamine moiety. The simulations show that this change in protonation leads to a lower absorption of doxorubicin to the MWCNTs. The MD studies were then experimentally validated, where functionalized MWCNTs showed improved dispersion in aqueous medium compared to pristine MWCNTs and, in agreement with the computational predictions, increased drug loading capacity. Doxorubicin-loaded functionalized MWCNTs demonstrated specific release of doxorubicin in tumor microenvironment (pH = 5.0) with negligible release in the physiological pH (pH = 7.4). Furthermore, doxorubicin-free MWNCT nanoformulations exhibited insignificant cytotoxicity. The experimental studies yielded nearly identical results to the MD studies, underlining the usefulness of the method. Our functionalized MWCNTs represent promising non-toxic nanoplatforms with enhanced aqueous dispersibility and the potential for conjugation with ligands for targeted delivery of anti-cancer drugs to breast cancer cells. Methods The computational model of a pristine carbon nanotube was created with the buildCstruct 1.2 Python script. The lysinated functionalized groups were added with PyMOL and VMD. The carbon nanotubes and doxorubicin molecules were parameterized using the general AMBER force field, and RESP charges were determined using Gaussian 09. Molecular dynamics simulations were carried out with the AMBER 20 software package. Adsorption levels were calculated using the water-shell function of cpptraj. Cytotoxicity was evaluated via a MTT assay using MDA-MB-231 and MCF-7 breast cancer cells. Drug uptake of doxorubicin and doxorubicin-loaded MWCNTs was measured by fluorescence microscopy.

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Dispersion and functionalization of single-walled carbon nanotubes (SWCNTS) for nanocomposite applications

Cited by 3 publications

References 38 publications

Acid-modified CNT/Zinc Oxide nanowires based high performance broadband photodetector

Acid-modified CNT/Zinc Oxide nanowires based high performance broadband photodetector

Poly(vinyl chloride)/Nanocarbon Composites for Advanced Potentiometric Membrane Sensor Design

In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin

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