General relationships applicable to a wide variety of bacterial mediated wastewater treatment processes have been developed using continuous-jlow stirred-tank reactors (CSTR) arranged in series. Monod kinetics and mathematical models of reactors-in-series were used to represent the actual conditions resulting from varying degrees of axial dispersion and wastewater qualities. A numerical method was developed and efluent concentrations from an equivalent reactor series expressed based upon a plug-flow reactor with the same inlet and outlet conditions. Using the numerical results obtained, a nomogram has been derived that enables the required hydraulic and solids residence times for a reactor with a given dispersion number to be determined, when inlet and outlet conditions and the coeficients of Monod kinetics are known.