Dispersion of Agglomerated Nanoparticles by Fine Beads Mill

Nanoparticulation of Poorly Water Soluble Drugs Using a Wet-Mill Process and Physicochemical Properties of the Nanopowders

“…In addition, it is considered that the ULTRA APEX MILL can suppress the thermal energy to lower level than other wet-mills using beads because of using finer zirconia beads (kinetic energy/beadϭ1/2 · mass · velocity 2 ). 16) It is generally considered that heat labile drugs are degraded by the heat generated during dry-milling. There are no reports in the literature of nanoparticulation of heat labile drugs without degradation by dry-or wet-milling.…”

“…ULTRA APEX MILL, which is a wet-mill using beads, is practically used primarily for inorganic substances such as titanium oxide or aluminum oxide to produce particles having nanometer size 16) and have wide production scale ranges from gram to kilogram (up to 20 kg). Wet-mill instruments using beads are usually equipped a screen type separater to isolate a wet-milled substrate from beads.…”

Characterization of Al2O3 Slurries Prepared by Wet Jet Milling

“…5 b . Generally, the peak of X-ray diffraction pattern is known to become broad by damage of crystal structures. 21 This indicates that Al 2 O 3 particles prepared by wet jet milling and ball milling are not damaged its crystal structure by milling. Figure 6 presents FT-IR diffuse reflection spectra of Al 2 O 3 particles before and after milling.…”

Fabrication of Highly Microstructure Controlled Ceramics by Novel Colloidal Processing

“…19 Here, it is noted that heavily-agglomerated particles cannot be re-dispersed by ultrasonic irradiation, 20 but recently it was confirmed that it can be re-dispersed by the beads milling technique using small 3YTZ beads less than 50 mm in diameter. 21 After evacuation in a desiccator to eliminate the air bubbles, the suspension was consolidated by slip casting. The obtained green compacts showed a narrow pore size distribution resulting in a low-tem- Figure 1 compares the tensile elongation of the 3YTZ polycrystal prepared by slip casting colloidal with the conventional dry processed polycrystal dry, in which the grain sizes of both samples are controlled to the same size of 0.22 mm.…”