For a solid surface or interface that is subjected to transverse loading, the influence of its flexural resistibility to bending deformation becomes significant. A spherical inhomogeneity or void embedded in an infinite elastic medium under the application of nonhydrostatic loads represents a typical example. In this work, we consider the most fundamental loading of a far-field unidirectional tension. Analytical displacements and stresses are developed by the coupling of a Steigmann–Ogden surface mechanical model, the simple method of Boussinesq displacement potentials, the semi-inverse method of elasticity, and Legendre series representations of spherical harmonics. The problem is then solved by converting the equilibrium equations of displacement into a linear system with respect to the Legendre series coefficients. The developed solutions are general in the sense that they may reduce to their classical or Gurtin–Murdoch counterparts as special cases. Analytical expressions reveal that the derived solution depends on four dimensionless ratios from among surface material parameters, shear moduli ratio, and inhomogeneity or void radius. In particular, instead of depending on both flexural parameters in the moment–curvature relation, one fixed combination is sufficient to represent the surface flexural rigidity. This is in contrast with the influence of the in-plane elastic stiffness, in which both surface Lamé parameters matter. Parametric studies further demonstrate that, for metallic inhomogeneities or voids with radii between 10 nm and 100 nm, the effects of surface flexural rigidity on stress distributions and stress concentrations are significant.