Disposable sensor based on enzyme-free Ni nanowire array electrode to detect glutamate

Jamal, Mamun; Hasan, Maksudul; Mathewson, A.; Razeeb, Kafil M.

doi:10.1016/j.bios.2012.07.024

Cited by 74 publications

(50 citation statements)

References 36 publications

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“…Recently, an enzyme-free method for the detection of glutamate was developed [5], but, unfortunately, this approach requires highly alkaline conditions for proper function. Therefore, the use of an enzyme is still required for glutamate detection in physiological pH.…”

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confidence: 99%

Glutamate detection by amino functionalized tetrahedral amorphous carbon surfaces

Kaivosoja

Tujunen

Jokinen

et al. 2015

Talanta

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In this paper, a novel amperometric glutamate biosensor with glutamate oxidase (GlOx) immobilized directly on NH2 functionalized, platinum doped tetrahedral amorphous carbon (ta-C) film, has been successfully developed. First, we demonstrate that direct GlOx immobilization is more effective on amino-groups than on carboxyl-or hydroxyl-groups. Second, we show that anodizing and plasma treatments increase the amount of nitrogen and the proportion of protonated 2 amino groups relative to amino groups on the aminosilane coating, which subsequently results in an increased amount of active GlOx on the surface. This effect, however, is found to be unstable due to unstable electrostatic interactions between GlOx and NH3 + . We demonstrate the detection of glutamate in the concentration range of 10 µM−1mM using the NH2 functionalized Pt doped ta-C surface. The biosensor showed high sensitivity (2.9 nA μM -1 cm -2 ), low detection limit (10 μM) and good storage stability. The electrode response to glutamate was linear in the concentrations ranging from10 µM to 500 µM. In conclusion, the study shows that GlOx immobilization is most effective on aminosilane treated ta-C surface without any pre-treatments and the fabricated sensor structure is able to detect glutamate in the micromolar range.

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confidence: 99%

Glutamate detection by amino functionalized tetrahedral amorphous carbon surfaces

Kaivosoja

Tujunen

Jokinen

et al. 2015

Talanta

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“…Such architectures are of interest for many applications, like drug delivery, bioanalysis, data and energy storage, sensors, and catalysis. [1][2][3][4][5][6][7][8][9][10] Recently, the magnetic field (MF)-assisted 11 self-assembly of magnetic colloids into organized nanostructures like fibers, chains, tubes, and circles [12][13][14] has attracted enormous attention. The studies demonstrated that a nanoscopic and mesoscopic orientational order can be achieved by application of an MF; however, the current strategies and the resulting assemblies do have specific stability aspects, which might be not compatible with some coveted applications.…”

Section: Introductionmentioning

confidence: 99%

Thermoreversible magnetic nanochains

et al. 2019

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“…Amino acid analysis is an important technique in many pharmaceutical, medical, chemical, food research, and industrial areas [1][2][3]. Thus far, various analytical methods have been proposed to determine amino acids, including high-performance liquid chromatography, capillary electrophoresis, enzyme assay, and chemical sensors [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. Usually, because of the weak light-absorptive property of amino acids, pre-or post-column derivatization with an appropriate labeling reagent is performed for determining amino acids with sensitivity and selectivity in HPLC with UV detection (HPLC-UV) and fluorescence detection (HPLC-FL) systems [9,10].…”

Section: Introductionmentioning

confidence: 99%

Voltammetric Determination of Amino Acids Based on the Measurement of Reduction Prepeak of Quinone Caused by Surplus Acid after Neutralization

et al. 2018

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In the voltammetric reduction of quinone, such as 3,5‐di‐tert‐butyl‐1,2‐benzoquinone (DBBQ), in the presence of HCl, a reduction prepeak of DBBQ caused by HCl can be observed on a voltammogram. Here, we have shown that the prepeak height of DBBQ is linearly decreased with increasing concentrations of amino acid in an electrolyte solution when this voltammetry is performed after neutralization between amino acids and excess HCl. This finding is based on a concept of acid‐base back titration of amino acids with excess HCl where surplus HCl gives a reduction prepeak of DBBQ. In this study, the reduction behaviors of DBBQ in the presence of amino acids and HCl have been provided to develop a novel electroanalytical method for the determining of amino acids. Electrochemical detection of 20 kinds of α‐amino acids, including less electroactive ones, has been achieved using a bare plastic formed carbon working electrode. Moreover, a flow injection analysis with electrochemical detection system using a glassy carbon working electrode is developed based on the present detection principle, and it has been applied to the determination of glutamine in an L‐glutamine granulated powder.

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Disposable sensor based on enzyme-free Ni nanowire array electrode to detect glutamate

Cited by 74 publications

References 36 publications

Glutamate detection by amino functionalized tetrahedral amorphous carbon surfaces

Glutamate detection by amino functionalized tetrahedral amorphous carbon surfaces

Thermoreversible magnetic nanochains

Voltammetric Determination of Amino Acids Based on the Measurement of Reduction Prepeak of Quinone Caused by Surplus Acid after Neutralization

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