2014
DOI: 10.1016/j.ejrad.2014.07.003
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Disrupted functional connectivity of the hippocampus in patients with hyperthyroidism: Evidence from resting-state fMRI

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Cited by 40 publications
(37 citation statements)
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“…Abnormal functional connectivity of DMN was reported to contribute to disrupted working memory [40, 41] and emotional processing [4244]. Previous studies of hyperthyroidism have revealed impaired metabolism and FC in brain regions anchored in DMN [7–9, 12, 13]. The related brain regions of DMN in hyperthyroidism primarily included PCC [8, 9, 12], inferior frontal gyrus [13] and superior frontal gyrus [7].…”
Section: Discussionmentioning
confidence: 99%
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“…Abnormal functional connectivity of DMN was reported to contribute to disrupted working memory [40, 41] and emotional processing [4244]. Previous studies of hyperthyroidism have revealed impaired metabolism and FC in brain regions anchored in DMN [7–9, 12, 13]. The related brain regions of DMN in hyperthyroidism primarily included PCC [8, 9, 12], inferior frontal gyrus [13] and superior frontal gyrus [7].…”
Section: Discussionmentioning
confidence: 99%
“…Previous studies of hyperthyroidism have revealed impaired metabolism and FC in brain regions anchored in DMN [7–9, 12, 13]. The related brain regions of DMN in hyperthyroidism primarily included PCC [8, 9, 12], inferior frontal gyrus [13] and superior frontal gyrus [7]. In the current study, we also found aberrant DMN functional connectivity in MeFG and PCu, and the FC between bilateral MeFG and PCu was negatively correlated with the processing speed Z scores.…”
Section: Discussionmentioning
confidence: 99%
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“…A functional magnetic resonance imaging (fMRI) study using the N‐back working memory task revealed altered activation in brain regions such as the parahippocampal gyrus, supplementary motor area, prefrontal cortex, anterior cingulate cortex, posterior cerebellum, rolandic operculum and insula in thyrotoxicosis . Similarly, an earlier resting state network FC study in thyrotoxicosis patients reported weak FC strength between the hippocampus and bilateral anterior cingulate cortex, posterior cingulate cortex and right medial orbitofrontal cortex using hippocampus as the seed region . Liu et al showed increased FC in the bilateral anterior insula, bilateral posterior insula and left anterior lobe of the cerebellum, as well as a decreased FC in the bilateral lateral prefrontal cortex, right medial temporal gyrus and bilateral posterior cingulate cortex to be associated with hyperthyroidism.…”
Section: Introductionmentioning
confidence: 97%
“…Previous neuroimaging studies have shown morphological, functional, metabolite and perfusion weighted changes associated with thyrotoxicosis. A functional magnetic resonance imaging (fMRI) study using the N‐back working memory task revealed altered activation in brain regions such as the parahippocampal gyrus, supplementary motor area, prefrontal cortex, anterior cingulate cortex, posterior cerebellum, rolandic operculum and insula in thyrotoxicosis .…”
Section: Introductionmentioning
confidence: 99%