Disruptive innovation in psychiatry

Abstract

Disruptive innovation is a cornerstone of various disciplines, particularly in the business world, where paradigmaltering approaches are often lauded. As a construct, disruptive psychiatry can be considered to embody such an approach by the pursuit of innovations within the field which test boundaries and shake up the status quo. Given the importance of addressing the current mental health pandemic, and the deficit of highly effective pharmacological treatments for various conditions, innovative disruptive thinking is required. Significant promise exists via the provision of potentially more effective innovative therapeutic options, including digital interventions, psychedelic medicines, microbiome-altering treatments, brain stimulation technology, and nanotechnology-based delivery systems. These approaches may be further advanced by individualization of the treatments using computational technology (including quantum computing, machine learning, and artificial intelligence) and genomics.

Quantum Computing and the Future of Neurodegeneration and Mental Health Research

“…Importantly, quantum computers may be capable of simulating the human brain more accurately than can be achieved employing standard methods. This information will help us identify disordered neural circuits and network dynamics, thereby providing critical information and leading to the development of targeted interventions [14,15]. Finally, quantum computing will likely enhance and refine predictive modeling strategies currently used to determine mental health outcomes.…”

“…However, an improved overall understanding of psychiatric disease will require extensive and computation-intensive analyses of complex datasets. Thus, quantum computing has the potential to improve our overall understanding of mental health and uncover new and personalized treatment strategies [14,15]. As noted earlier, quantum computing algorithms may accelerate drug discovery because they can generate simulations of complex molecular events and interactions more rapidly and accurately than can be achieved using standard computing technology.…”

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“…Disruptive technologies have potential to radically transform the paradigms, norms, legislation, and service delivery methods (Hopster, 2021). AI and robotic technology are disruptive innovations that can revolutionize the paradigm of mental health services (Bickman, 2020;Sarris, 2022). Reflecting on the last 50 years of mental health services, Bickman (2020) argues that AI holds promises in addressing problems such as diagnostic issues and treatment inadequacies.…”

Nutraceuticals and phytoceuticals for treating psychiatric disorders: a synopsis of the WFSBP and CANMAT 2022 clinician guidelines

“…Many factors were raised as needing to be considered when prescribing these agents. These include differences in treatment history, clinical presentation, biomarker data, and regard to co-use with emerging technologies (5). With respect to brands, this can entail considerable ambiguity for both clinicians and consumers.…”