Radio mini-haloes are a poorly-understood class of moderately-extended diffuse radio source that trace the presence of magnetic fields and relativistic electrons on scales of hundreds of kiloparsecs, predominantly in relaxed clusters. With relatively few confirmed detections to-date, many questions remain unanswered. This paper presents new radio observations of the galaxy cluster MS 1455.0+2232 performed with MeerKAT at 1283 MHz and LOFAR at 145 MHz, the first results from a homogeneously selected mini-halo census. We find that the mini-halo in MS 1455.0+2232 extends for around 590 kpc at 1283 MHz, significantly larger than previously believed, and has a flatter spectral index (𝛼 = −0.97 ± 0.05) than is typically expected. Our X-ray analysis clearly reveals a large-scale (∼ 254 kpc) sloshing spiral in the intracluster medium. We perform a point-to-point analysis, finding a tight single correlation between radio and X-ray surface brightness, indicating a strong link between the thermal and non-thermal components of the intracluster medium. Conversely, in the spectral index/X-ray surface brightness plane, we find that regions inside and outside the sloshing spiral follow different correlations. We find compelling evidence for multiple sub-components in this mini-halo for the first time. While both the turbulent (re-)acceleration and hadronic scenarios are able to explain some observed properties of the mini-halo in MS 1455.0+2232, neither scenario is able to account for all the evidence presented by our analysis.