Disseminated Candidiasis in Two HIV-Positive Intravenous Drug Users

Ruiter, Annemiek de; Lloyd, Mark; Wood, Cg; Graham, Elizabeth; Bingham, J S

doi:10.1177/095646249500600114

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…This patient was a drug abuser and had candida cultured from an area of cellulitis on the left leg. Candida endophthalmitis in HIV-positive patients has been previously reported by De Ruiter et al 21 . Both of her patients, of which case 7 was one, were intravenous drug abusers.…”

Section: Discussionmentioning

confidence: 86%

Symptomatic Anterior Uveitis in HIV-Positive Patients

et al. 1999

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Symptomatic anterior uveitis is rare in HIV-positive patients. The uveitis associated with cytomegalovirus retinitis (CMVR), the commonest ocular manifestation in AIDS patients, is rarely symptomatic and patients do not typically present with a red painful eye in conjunction with blurred vision. In this article we report 12 cases of symptomatic anterior uveitis in HIV-positive patients and discuss the aetiology. The case notes of all HIV-positive patients presenting to the eye department with symptoms of uveitis over a 4-year period were studied retrospectively. The notes were analysed for age, sex, race, risk factors of HIV, features of the uveitis, concurrent disease and CD4 counts. Only 12 patients were identified to have symptomatic uveitis out of a total 172 patients. There were 9 males and 3 females with an average age of 35 years. None of these patients were taking either rifabutin, protease inhibitors or cidofovir. Seven out of the 12 patients had granulomatous uveitis. Of these 7 patients, 4 had CD4 counts over 200 and no other concurrent illness whilst 3 patients, with CD4 counts between 130-200, were subsequently found to have an underlying aetiology namely lymphoma, tuberculosis and candida. The remaining 5 patients, all with CD4 counts below 40, had a history of systemic illness with herpes zoster preceding the onset of the uveitis. HIV-positive patients with symptoms of uveitis do not have active CMVR and the ophthalmologist must search for other causes such as tuberculosis or lymphoma in those with granulomatous uveitis or herpes zoster in those with non-granulomatous uveitis. The CD4 count may be helpful.

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Section: Discussionmentioning

confidence: 86%

Symptomatic Anterior Uveitis in HIV-Positive Patients

et al. 1999

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“…The costosternal joints were involved in most cases and C. albicans was isolated from blood cultures in one patient. Three reports from London suggest a link between the injection of brown heroin in lemon juice and arthritis due to C. albicans , again the costosternal joints being involved in association with cutaneous nodules 6 . In Barcelona 1 and Paris 9 a clinical syndrome has been described involving cutaneous, ocular and osteoarticular manifestations after the injection of brown heroin dissolved in lemon juice.…”

Section: Discussionmentioning

confidence: 99%

“…C. albicans septic arthritis in HIV‐infected individuals was first described in 1991 by Edelstein and McCabe 5 . Since then several cases have been described, all in injecting drug users (IDU) 6–8 . We report the first case in a non‐IDU HIV‐positive bisexual man.…”

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confidence: 94%