Disseminated cryptococcosis with skin lesions: report of a case series

Hayashida, Marina Zoéga; Seque, Camila Arai; Pasin, Victor Pavan; Enokihara, Mílvia Maria Simões e Silva; Porro, Adriana María

doi:10.1590/abd1806-4841.20176343

Cited by 21 publications

(18 citation statements)

References 9 publications

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“…The common initial sites of Cryptococcal infection include the lung and the brain, which primarily suggests pathogenesis through the respiratory tract. However, various infection sites reported on the skin, lung, parotid, muscle, breast, or mediastinal abscess in the literature favors the hypothesis of hematogenous or lymphatic dissemination [ 5 , 11 , 12 ]. In the present reported patient, the culture of blood, CSF, and breast aspiration were positive, which proved hematogenous spreading and might explain why the breast infection was bilateral, and diffuse.…”

Section: Discussionmentioning

confidence: 99%

Imaging of cryptococcus neoformans infection in breasts: A case report

Hà

Huong

Trang

et al. 2021

Radiology Case Reports

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There have been few reports on the imaging characteristics of cryptococcus neoformans (C. neoformans ) infection of the breast. Herein, we reported the imaging features of C. neoformans infection of the breast in a 41-year-old woman with immune thrombocytopenic purpura. Bilateral, diffuse, hyperechoic, and well-defined margin lesions were observed on breast ultrasounds. In addition, a global asymmetry in the left breast, and a focal asymmetry in the right breast were observed on mammograms. Breast fine needle aspiration and biopsy results revealed a C. neoformans infection. After 5 months of treatment with oral fluconazole and amphotericin B, the lesion on the right breast disappeared on repeated-breast ultrasounds.

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Section: Discussionmentioning

confidence: 99%

Imaging of cryptococcus neoformans infection in breasts: A case report

Hà

Huong

Trang

et al. 2021

Radiology Case Reports

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“…In turn, C. neoformans most often affects immunocompromised patients, e.g. those with AIDS and organ transplant recipients (Hayashida et al 2017;Zhang et al 2019). The cutaneous manifestations may include nodules, papules, pustules, abscesses, subcutaneous swelling, cellulitis-like erythema, and pyoderma gangrenosum-like ulcerations (Table 1) (Kikuchi et al 2016;Hayashida et al 2017).…”

Section: Cryptococcosismentioning

confidence: 99%

“…those with AIDS and organ transplant recipients (Hayashida et al 2017;Zhang et al 2019). The cutaneous manifestations may include nodules, papules, pustules, abscesses, subcutaneous swelling, cellulitis-like erythema, and pyoderma gangrenosum-like ulcerations (Table 1) (Kikuchi et al 2016;Hayashida et al 2017). Disseminated infection should always be ruled out in patients with cutaneous cryptococcosis (Perfect et al 2010).…”

Section: Cryptococcosismentioning

confidence: 99%

A global view on fungal infections in humans and animals: opportunistic infections and microsporidioses

et al. 2021

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After cardiovascular diseases, infectious diseases are the second most common cause of death worldwide. Although these infections are caused mainly by viruses or bacteria, a systematically growing prevalence of human and animal opportunistic fungal infections is noticeable worldwide. More attention is being paid to this problem, especially due to the growing frequency of recalcitrant and recurrent mycoses. The latter are classically divided into superficial, which are the most common type, subcutaneous, and systemic. This work discusses opportunistic fungal pathogens without proven horizontal transmission between different animal species including humans and microsporidia as spore-forming unicellular parasites related to fungi; however, with a yet undetermined taxonomic position. The review also mentions etiological agents, risk factors, epidemiology, geographical distribution, and finally symptoms characteristic for individual disease entities. This paper provides insight into fungal infections from a global perspective and Accepted Article This article is protected by copyright. All rights reserved simultaneously draws attention to emerging pathogens, whose prevalence is continuously increasing. Finally, this work also takes into consideration the correct nomenclature of fungal disease entities and the importance of secondary metabolites in the pathogenesis of fungal infections.

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“…Virginia Velasco-Tamariz 1 , Raquel Aragón-Miguel 1 , Elena Gutiérrez-Solís 2 , Mónica Milla-Castellanos 2 , Francisco López-Medrano 3 , Laura Corbella-Vazquez 3 , Raúl Recio-Martínez 4 , Alfredo Pérez-Rivilla 4 , José Luis Rodríguez-Peralto 5 , Pablo Luis Ortiz-Romero 1 , Carlos Zarco-Olivo 1…”

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