Disseminated cutaneous sporotrichosis

Sharon, Victoria R.; Kim, Jeanyoung; Sudhakar, Shiv; Fung, Maxwell A.; Maniar, Archana

doi:10.1016/s1473-3099(12)70140-8

Cited by 12 publications

(13 citation statements)

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“…In this case, the likely contributing factor of the spread of the fungus was the alcoholism. Our report corroborates the association previously reported by other authors 7,9,10,11 between alcoholism and the spread of sporotrichosis.…”

Section: Discussionsupporting

confidence: 93%

Disseminated cutaneous sporotrichosis in patient with alcoholism

Benvegnú

Stramari

Dallazem

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Sporotrichosis is the most prevalent subcutaneous mycosis and is characterized by a subacute or chronic development of a cutaneous or subcutaneous nodular lesion. It is caused by the dimorphic fungus Sporothrix spp, which may manifest in different clinical forms. The disseminated cutaneous form is uncommon and is more likely to occur in immunocompromised patients. We report a 47-year-old male patient with multiple cutaneous and subcutaneous nodules. The patient was diagnosed with disseminated cutaneous sporotrichosis based on the isolation and identifi cation of Sporothrix spp. The patient was treated with potassium iodide, which resulted in clinical improvement of the lesions.

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Section: Discussionsupporting

confidence: 93%

Disseminated cutaneous sporotrichosis in patient with alcoholism

Benvegnú

Stramari

Dallazem

et al. 2017

Rev. Soc. Bras. Med. Trop.

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“…How do they conduct complicated human cases and those presenting atypical clinical manifestations such as the ones described in recent years? [ 20 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ]. Although the increase in the number of cases has been accompanied by problems for the health system, it has created opportunities to produce knowledge and to deepen the study of human and animal cases that were previously scarce.…”

Section: The Global Increase Of Sporotrichosis Creates New Problemmentioning

confidence: 99%

Immunopathogenesis of Human Sporotrichosis: What We Already Know

Conceição-Silva

Morgado

2018

JoF

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Sporotrichosis is a subacute/chronic mycosis caused by dimorphic fungus of the genus Sporothrix. This mycosis may affect both human and domestic animals and in the last few years, the geographic dispersion and increase of sporotrichosis worldwide has been observed. The occurrence of cases related to scratching/bites of domestic felines have increased, characterizing the disease as predominantly a zoonosis. In humans, sporotrichosis mainly involves the cutaneous tegument of infected patients, but other tissues may also present the infection. The main forms of clinical presentation are lymphocutanous sporotrichosis (LC) and fixed sporotrichosis (F). Although less common, mucosal, cutaneous disseminated, and extracutaneous forms have also been described. Multiple factors from the fungus and host can play a role in driving the clinical evolution of sporotrichosis to benign or severe disease. In this review, we discuss the immunopathological aspects involved in human sporotrichosis. Putting together the two branches of knowledge—host immune response and fungal evading mechanisms—we may perceive new possibilities in understanding the fungus–host interaction in order to be in a position to go further in the control of sporotrichosis.

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“…La enfermedad en humanos usualmente compromete la piel incluyendo el tejido celular subcutáneo (TCSC) y vasos linfáticos vecinos pero, en personas inmunocomprometidas, suele afectar también otros órganos [1][2][3][4] . La presentación clínica puede variar de acuerdo al estado inmunológico del hospedero 1,3,4 , de la carga fúngica, profundidad y lugar del inóculo, así como de la patogenicidad y tolerancia térmica de la cepa, de la especie y del genotipo 5-7 . La distribución geográfica de esta micosis es universal, predominando en lugares de clima cálido y templado. Es endémica en Sudáfrica 8 , India 9 , Japón 10 , Estados Unidos de América (E.U.A.)…”

Section: Introductionunclassified