Disseminated Gonorrhea Presenting as Liver Abscess in a Patient With Sickle Cell Disease

Kim, Jani M; Pervaiz, Sarah; Sivasubramanian, Geetha

doi:10.1097/olq.0000000000001624

Cited by 1 publication

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Certain strains like protein 1A serotype and those lacking protein II and arginine-uracil are more prone to cause disseminated infection in the absence of urethral symptoms which is explained by their less potent inflammatory response [6]. In the literature, there are reports of gonococcal bacteremia with unusual sites of infections including liver abscess, meningitis, and endocarditis [7][8][9][10][11]. This includes a case of a young female with sickle cell disease and without prior genitourinary complaints presenting as gonococcal liver abscess as well as another case of gonococcal bacteremia associated with a liver abscess in a patient without any known risk for dissemination.…”

Section: Discussionmentioning

confidence: 99%

Disseminated Gonococcal Infection Due to a Mediport Catheter Infection

Malik,

Peniston,

Donaghue

et al. 2023

Cureus

View full text Add to dashboard Cite

Gonorrhea is a sexually transmitted disease caused by Neisseria gonorrhoeae and has a wide clinical spectrum that can range from asymptomatic to disseminated disease. Most women with gonorrhea are asymptomatic and if left untreated, it can lead to serious complications like pelvic inflammatory disease (PID) and infertility. Disseminated gonococcal infection (DGI) is usually characterized by dermatitis, tenosynovitis, and septic arthritis but rarely can also cause bacteremia, endovascular infections, osteomyelitis, and meningitis. Gonococcal bacteremia is regarded as a disseminated disease and is typically associated with infection of the mucosal surfaces such as the urethra, endocervix, and pharynx. This report, to the best of our knowledge, presents a case of DGI associated with a mediport catheter in a patient with breast cancer without any history of gonococcal symptoms. She was monogamous and denied any history of sexually transmitted infections. The patient presented with fever and chills associated with pain and purulent discharge from the mediport catheter site. The mediport catheter was removed, and antibiotics were initiated. Both blood and wound cultures grew N. gonorrhoeae . She completed a 10-day course of ceftriaxone and improved clinically with complete remission of her symptoms. A review of the literature on the reported cases of DGI associated with bacteremia and endovascular infections is also presented.

show abstract