Disseminated Inflammatory Lesions in 2 COVID-19 Patients: Challenge

Abstract

T wo patients with COVID-19 infection and no previous contact were admitted to our hospital, presenting with a similar cutaneous eruption.

Eruptive Pruritic Maculopapular Rash Following Pfizer-BioNTech COVID-19 Vaccination: Answer

“…Attributed to molecular mimicry and upregulated inflammatory, immunological pathways, it has been postulated that COVID-19 vaccines might contribute to immune-mediated phenomena, either exacerbating the preexisting or new onset of immune-mediated disorders. 17 In consistency with initial considerations in support of an immunological response against abnormal clones of keratinocytes as the underlying cause of eruptive pruritic papular porokeratosis, 13,14 Fernandez-Figueras et al 18,19 postulated that COVID-19 infection might have triggered an immune response related to the intensification of an inflammatory reaction against mutated clones from preexisting porokeratotic lesions.…”