Disseminated Peritoneal Leiyomyomatosis in an 18-Year-Old Girl

Arneja, Sarabjeet Kaur

doi:10.1016/j.jpag.2010.06.001

Cited by 4 publications

(7 citation statements)

References 8 publications

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“…They were all resected and the histopathological findings revealed adenosarcoma with stromal overgrowth. Arneja et al [8] reported a similar case in a 18 year old female who had undergone several laparoscopic surgical resections of uterine leiyomyomas. In this case the histopatological report showed a peritonealy disseminated leiomyomatosis; peritoneal dissemination in a benign tumor was explained by the presence of smooth muscle metaplasia of subperitoneal mesenchymal stem cells of the secondary müllerian system.…”

Section: Description Of Histopathological Resultsmentioning

confidence: 85%

Hemoperitoneum from Ruptured Uterine Tumor Invading Ileal Mesentery and Mesosigmoid Case report and literature review

Bacalbaşa¹,

Cirlan²,

Sas³

et al. 2018

Mat.Plast.

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Uterine sarcomas are rare but very aggressive gynecologic malignancies. The most frequent signs and symptoms at the moment of diagnosis include abnormal uterine bleeding or diffuse abdomino-pelvic pains while acute abdomen by uterine rupture is an uncommon situation. We present the case of a 72 year old patient who presented in emergency for diffuse abdominal pain and hypotension. An emergency laparotomy was performed and a ruptured uterine tumor with small bowel and sigmoidian serosal invasion and intra-peritoneal bleeding was found. The tumor was resected en bloc with total hysterectomy, bilateral adnexectomy, segmental enterectomy and sigmoidectomy, pelvic and para-aortic lymph node dissection. The histopathological and immunohistochemistry examination revealed a poorly differentiated sarcoma. Although it is a rare condition, a uterine sarcoma can rupture and cause hemoperitoneum; emergency surgery while respecting oncologic principles of complete resection is mandatory.

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Section: Description Of Histopathological Resultsmentioning

confidence: 85%

Hemoperitoneum from Ruptured Uterine Tumor Invading Ileal Mesentery and Mesosigmoid Case report and literature review

Bacalbaşa¹,

Cirlan²,

Sas³

et al. 2018

Mat.Plast.

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“…Cases of disseminated peritoneal leiomyomatosis after robotic, laparoscopic and open+ power morcellation have been reported (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32). These tumors may be found incidentally during surgery and are often diffuse throughout the abdomen, involving multiple structures; therefore an intra operative consultation may be required.…”

Section: Resultsmentioning

confidence: 99%

“…As discussed previously, an increase in hormone levels and the response of susceptible smooth muscle cells have been suggested as a cause of these tumors [6]. However, several cases have been reported of iatrogenic dissemination after morselization either post robotic or laparoscopic surgery [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. As these tumors are normally discovered as an incidental finding, histology and peritoneal washing play an important role in diagnosis and ruling out malignancy.…”

Section: Discussionmentioning

confidence: 99%

“…As these tumors are normally discovered as an incidental finding, histology and peritoneal washing play an important role in diagnosis and ruling out malignancy. DPL tumors are traditionally considered benign but several cases of malignant transformation have been reported, many occurring after surgical treatment [18][19][20][21][22][23][24][25][26]. In this case, a portion of the tumor was resected and sent for pathological analysis prior to follow up and further management.…”

Section: Discussionmentioning

confidence: 99%

“…These include avoiding oral contraceptives (OCP) and hormone replacement therapy (HRT) [10], administering gonadotropin releasing hormone agonist aromatase inhibitor therapy [28,29] and avoiding pregnancy . Without proper treatment, DPL can cause complications such as pain, bleeding, chronic constipation and infertility [17][18][19][20][21][22][23][24][25][26][27][28][29][30]. Therefore management of DPL should be patient centered in order to achieve the specific treatment goals for each patient depending on their future plans for pregnancy.…”

Section: Discussionmentioning

confidence: 99%

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Disseminated Peritoneal Leiomyomatosis (DPL); A Case Report and Review of Literature

Rezai¹

2017

OGIJ

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Background: Disseminated peritoneal leiomyomatosis (DPL) also known as leiomyomatosis peritonealis disseminate (LPD) is a rare condition described as multiple smooth muscle tumors disseminated throughout the peritoneum, omentum and pelvic structures. Since first being described in 1952, less than 150 cases have been reported in English literature. However, the incidence of DPL may be under estimation as many cases are asymptomatic. The lesions occur most commonly in women of child bearing age and may have an association with oral contraceptive therapy (OCP) or hormone replacement therapy (HRT). These diffuse tumors are usually incidentally found during surgery but women may present with abdominal pain prompting investigation. This condition is rarely reported; therefore we describe a case of DPL in a 35 year old woman incidentally found during cesarean delivery.

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