Dissipation pattern of azoxystrobin and difenoconazole in red dragon fruit (Hylocereus polyrhizus) cultivated in Indonesian highland (West Java) and coastal area (D.I. Jogyakarta) and its implication for dietary risk assessment

Noegrohati, Sri; Sulasmi, Sri; Hernadi, Elan; Asviastuti, Syanti

doi:10.1093/fqsafe/fyz009

Cited by 16 publications

(7 citation statements)

References 13 publications

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“…Nevertheless, information on what chemicals and their effectivity are not widely reported. Azoxystrobin and difenoconazole have been shown to control anthracnose and stem canker (Noegrohati et al 2019). Hexaconazole, tebuconazole, flusilazole, and pyraclostrobin inhibit N. dimidiatum growth (Xu et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Fruit brown rot caused by Neoscytalidium dimidiatum on Selenicereus monacanthus in the Philippines

Balendres¹,

Taguiam²,

Evallo³

et al. 2022

MycoAsia

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Multiple fungal pathogens infect economically important fruits, thereby affecting their quality and marketability. Previous research showed that some fungal pathogens that can infect the stems might infect the fruit but show a different symptom. To determine the causal pathogen of a fruit disease of Selenicereus monacanthus (Dragon fruit), we used a combination of fungal pathology characterization and molecular biology techniques. This paper presents the pathogenicity of Neoscytalidium dimidiatum MBDF36C to S. monacanthus resulting in brown rot and canker on fruits and stem, respectively. The paper also demonstrates the in vitro inhibition of N. dimidiatum MBDF36C by chemicals, including a bio-fungicide containing Bacillus subtilis. At seven days post-inoculation, we observed severe browning on N. dimidiatum MBDF36C-inoculated fruits but not on stems. Stems exhibited canker-like symptoms. The same fungus was re-isolated from both inoculated diseased fruits and stems, thereby confirming Koch's postulates. The pathogen was identified as N. dimidiatum based on its morphology, cultural characteristics, and sequences of the partial ß-tubulin gene. In vitro growth of N. dimidiatum MBDF36C was also completely inhibited by a bio-fungicide containing B. subtilis, isoprothiolane, and mancozeb. This study is the first report of N. dimidiatum causing brown fruit rot of dragon fruit in the Philippines. This information could impact the current postharvest fruit handling operations and future studies on dragon fruit disease management

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Section: Discussionmentioning

confidence: 99%

Fruit brown rot caused by Neoscytalidium dimidiatum on Selenicereus monacanthus in the Philippines

Balendres¹,

Taguiam²,

Evallo³

et al. 2022

MycoAsia

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“…Interestingly, one of the compounds tested is a known broad-spectrum fungicide; Difenoconazole (MMV688943-C06A) with a proven preventive and curative usage against some diseases in fruits, vegetables, cereals and other field crops. It acts by inhibition of demethylation during ergosterol synthesis [ 37 , 38 ]. In this study we suggest its repurposing as an antileishmanial drug candidate due to its selective bioactivity against L .…”

Section: Discussionmentioning

confidence: 99%

Some novel antileishmanial compounds inhibit normal cell cycle progression of Leishmania donovani promastigotes and exhibits pro-oxidative potential

et al. 2021

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In the midst of numerous setbacks that beclouds the fight against leishmaniasis; a neglected tropical disease, the search for new chemotherapeutics against this disease is of utmost importance. Leishmaniasis is a disease closely associated with poverty and endemic in Africa, Asia, southern Europe and the Americas. It is caused by parasites of the genus Leishmania and transmitted by a sandfly vector. In this study, we evaluated the antileishmanial potency of eighteen pathogen box compounds and elucidated their biosafety and possible mechanisms of action against Leishmania donovani promastigotes and amastigotes in vitro. IC50s range of 0.12±0.15 to >6.25 μg/ml and 0.13±0.004 to >6.25μg/ml were observed for the promastigotes and amastigotes, respectively. We demonstrated the ability of some of the compounds to cause cytocidal effect on the parasites, induce increased production of reactive oxygen species (ROS), disrupt the normal parasite morphology and cause the accumulation of parasites at the DNA synthesis phase of the cell cycle. We recommend a further in vivo study on these compounds to validate the findings.

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“…The dose of the fungicide was applied according to the product recommendation. The fertilisation regime and other cultural practices followed the recommendations by the Directorate General of Horticulture (Direktorat Jendral Hortikultura) (Noegrohati et al 2019).…”

Section: In Vitro Antifungal Assaymentioning

confidence: 99%

Stem canker of dragon fruit (Hylocereus polyrhizus): Neocytalidium sp. is the new cause of the disease and its control using the sodium salt

Riska¹,

Jumjunidang²,

Budiyanti³

et al. 2023

Plant Prot. Sci.

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Dragon fruit (Hylocereus sp.) or pitaya is a type of cactus that has potential as a "cash fruit" in Indonesia. This exotic plant is native to Latin (North and Central) America and was introduced to Indonesia in the 1990s. The agribusiness of this fruit grew rap-idly at a farmer level in a short time; besides being easy to cultivate, it also has numerous selling points for the market such as its unique shape and attractive colour (Le Bellec et al. 2006). Red-fleshed dragon fruit (H. polyrhizus) is the most popular species,

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Dissipation pattern of azoxystrobin and difenoconazole in red dragon fruit (Hylocereus polyrhizus) cultivated in Indonesian highland (West Java) and coastal area (D.I. Jogyakarta) and its implication for dietary risk assessment

Cited by 16 publications

References 13 publications

Fruit brown rot caused by Neoscytalidium dimidiatum on Selenicereus monacanthus in the Philippines

Fruit brown rot caused by Neoscytalidium dimidiatum on Selenicereus monacanthus in the Philippines

Some novel antileishmanial compounds inhibit normal cell cycle progression of Leishmania donovani promastigotes and exhibits pro-oxidative potential

Stem canker of dragon fruit (Hylocereus polyrhizus): Neocytalidium sp. is the new cause of the disease and its control using the sodium salt

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