Dissociation of osmoregulation from plasma arginine vasopressin levels following thermal injury in childhood

Acute hospital-induced hyponatremia in children: A physiologic approach

“…Patients become alert, able to converse, and able to drink water. 21 ADH is suppressed 22 ; despite oral water intake, serum sodium remains normal. 23 As inflammation subsides in the succeeding 24 hours, the ''extra'' ECF is recovered into plasma and excreted as urine.…”

Fluid therapy for children: facts, fashions and questions

“…50 Children with severe burn shock had extreme elevations of antidiuretic hormone on admission; with aggressive extracellular expansion, these levels fell over 12 h to near normal values. 51 Children with acute diarrhoeal dehydration had elevated antidiuretic hormone levels on admission which declined after 4 h of extracellular fluid expansion, but not always to normal. The above findings have led us to conclude that the non-osmotic stimulation of antidiuretic hormone seen in acutely ill children is often due to hypovolaemia.…”

Συσχέτιση παραγόντων ψυχονοητικού και κυτταρικού stress στο σύνδρομο πολυοργανικής δυσλειτουργίας (mods) βαριά πάσχοντα

“…Τα χαμηλά επίπεδά της στη σήψη ενδεχόμενα οφείλονται σε μείωση των υποφυσιακών αποθεμάτων (Sharshar et al 2002). Αντιθέτως, τα επίπεδα της AVP μπορεί να αυξηθούν στα εγκαύματα (McIntosh et al 2000). Επιπλέον, σημαντικότερη αύξηση στις τιμές της AVP στο πλάσμα (Padilla et al 1989, Huang et al 2001, που σχετίζονται με την έκταση του τραύματος (Yang et al 2002), έχουν αναφερθεί σε ασθενείς με οξύ εγκεφαλικό.…”