Dissolution of retained duct stones by perfusion with monooctanoin via a Teflon catheter introduced endoscopically

Duodenoscopic Transpapillary Techniques and Results in Biliary and Pancreatic Diseases: An Update

“…In addition, the tube can be irrigated with solutions to help expel stones. Solvents such as monooctanoin can be perfused via the N-B tube to shrink large stones and facilitate passage [56][57][58]. Nasobiliary drainage is especially valuable for temporary drainage of obstruction due to benign or malignant bile duct lesions.…”

Nonoperative Management of Retained Common Bile Duct Calculi with Mono-Octanoin

“…There is a choice between reoperation, endoscopic sphincterotomy, [4][5][6][7][8][9][10] Dormia basket extraction through the T-tube tract, 11,12 and infusion of monooctanoin through the T-tube to fragment and dissolve retained stones. [13][14][15][16][17][18] Thistle and colleagues 18 screened solvents to find a safe agent with high capacity for cholesterol monohydrate solubilization. Before that, sodium cholate was used as a cholesterol solvent but required perfusion for several weeks to bring about complete stone dissolution.…”

“…15,18,[23][24][25] The aim of this study was to find a convenient method of mono-octanoin infusion, to confirm its efficacy in dissolution of radiolucent retained common bile duct stones, to find a means to reduce the incidence of side effects, and to define eligibility for this treatment.…”