“…Cap-assisted colonoscopy first appeared in Japan in the 1990 s and since then, its use for diagnostic colonoscopy has been slowly gaining acceptance, supported by technical developments and new devices showing incremental benefit in terms of adenoma yield, an established surrogate for colorectal cancer-related mortality 1 . While the first-generation Endocuff has not been shown to be effective in this context 2 and aggregate gains from Endocuff-assisted colonoscopy (EAC) have been considered to be equivocal in comparison to standard colonoscopy (SC) 3 and transparent cap-assisted colonoscopy (TAC) 4 5 , recent high-quality evidence supports the utility of the next-generation Endocuff Vision (ECV, Olympus Japan) in the context of colon cancer screening 6 7 .…”