Distinct impact modes of polygenic disposition to dyslexia in the adult brain
Sourena Soheili-Nezhad,
Dick Schijven,
Rogier B. Mars
et al.
Abstract:Dyslexia is a common condition that impacts reading ability. Identifying affected brain networks has been hampered by limited sample sizes of imaging case-control studies. We focused instead on brain structural correlates of genetic disposition to dyslexia in large-scale population data. In over 30,000 adults (UK Biobank), higher polygenic disposition to dyslexia was associated with lower head and brain size, and especially reduced volume and/or altered fiber density in networks involved in motor control, lang… Show more
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