Distinctive Clinical Features of “Anxious-Depressive Attack”

Kaiya, Hisanobu

doi:10.14389/jsad.9.1_2

Cited by 10 publications

(39 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…e diagnosis of SAD was assessed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR; American Psychiatric Association, 2000). e presence or absence of ADA was con rmed according to criteria for ADA diagnosis (Table 1), as used previously (Kaiya, 2017). e con rmation was conducted by a psychiatrist during a clinical evaluation.…”

Section: Methodsmentioning

confidence: 99%

“…Liebowitz (1987) stated that patients with social anxiety disorder (SAD) appear hypersensitive to rejection or criticism, suggesting an overlap with atypical depression or hysteroid dysphoria, where rejection sensitivity (RS) is a noticeable feature. e study by Kaiya (2017) further showed that the occurrence rate of ADA was highest in depression with atypical features (DAF). Parker and ase (2007) pointed out that RS was a better diagnosing factor than mood reactivity in DAF.…”

Section: Introductionmentioning

confidence: 99%

“…Anxious-depressive attack (ADA) is a poorly studied symptom cluster associated with anxiety and mood disorders (Kaiya, 2016(Kaiya, , 2017. In ADA, the following symptoms appear sequentially over time: (1) sudden intense distressing emotions without a direct psychological cause;…”

Section: Introductionmentioning

confidence: 99%

“…(2) obstinate, intrusive ruminative thinking of various events with a mostly unhappy nature, Original Article o en accompanied by ashbacks; (3) intense worry, unrest, and forlornness against the negative details of the situations; and (4) in most cases, various coping behaviors, including acting out. ADA is not considered a panic attack given the lack of intense physical symptoms (Kaiya, 2016(Kaiya, , 2017. ADA has been observed in various mental disorders, mainly in internalizing disorders, but has been ignored for a long time because most patients do not voluntarily report ADA symptoms.…”

Section: Introductionmentioning

confidence: 99%

“…According to a previous study of outpatients at our clinics with symptoms of anxiety and depression, patients with ADA showed higher scores on the Liebowitz Social Anxiety Scale (LSAS) than those without ADA irrespective of the diagnosis (Kaiya, 2017). Liebowitz (1987) stated that patients with social anxiety disorder (SAD) appear hypersensitive to rejection or criticism, suggesting an overlap with atypical depression or hysteroid dysphoria, where rejection sensitivity (RS) is a noticeable feature.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Effects of Rejection Sensitivity on the Development of Anxious-Depressive Attack in Patients with Social Anxiety Disorder

et al. 2020

Self Cite

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effects of Rejection Sensitivity on the Development of Anxious-Depressive Attack in Patients with Social Anxiety Disorder

et al. 2020

Self Cite

View full text Add to dashboard Cite

Anxious‐depressive attack and rejection sensitivity—Toward a new approach to treatment‐resistant depression

Kaiya

2023

Neuropsychopharm Rep

Self Cite

View full text Add to dashboard Cite

This paper aimed to find clues to treatment‐resistant depression (TRD) solutions. Depression comorbid with anxiety is often treatment‐resistant where anxious‐depressive attack (ADA) often lurks. ADA is a recently proposed clinical idea for just a psychological version of a panic attack. It mostly begins with an abrupt surge of intense anxiety followed by uninterrupted intrusive thoughts; lasting ruminations about regret or worry produced by violent anxiety, agitation, and loneliness. Acting‐out behaviors such as deliberate self‐injury and over‐dose may also be observed during the attack. As the basic psychopathology of ADA, rejection sensitivity (RS) was revealed by a structural equation model. It is said that the presence of RS in depressive disorders implies a poor prognosis. The following biological markers for RS were reviewed in the literature: first, the involvement of the μ‐opioid receptor function in RS and, secondly, hypersensitivity of the dopamine D4 receptor (DRD4) in the medial prefrontal cortex. The latter has been suggested in fear‐conditioned animal experiments. Manipulation of the μ‐opioid receptor function together with the DRD4 function may culminate in a treatment for RS, which could contribute to the development of a treatment for TRD via the improvement of ADA.

show abstract

Evaluating psychological distress associated with life events under the traumatic experience threshold in patients with major depressive and bipolar disorder

Ishii,

Hashimoto,

Sato

et al. 2024

Sci Rep

View full text Add to dashboard Cite

Patients with bipolar disorder (BD) and major depressive disorder (MDD) experience psychological distress associated with daily events that do not meet the threshold for traumatic experiences, referred to as event-related psychological distress (ERPD). Recently, we developed an assessment tool for ERPD, the ERPD-24. This tool considers four factors of ERPD: feelings of revenge, rumination, self-denial, and mental paralysis. We conducted a cross-sectional study between March 2021 and October 2022 to identify the differences and clinical features of ERPD among patients with MDD and BD and healthy subjects who did not experience traumatic events. Specifically, we assessed ERPD using the ERPD-24 and anxiety-related symptoms with the State-Trait Anxiety Inventory, Liebowitz Social Anxiety Scale, and anxious-depressive attack. Regarding the ERPD-24 scores among the groups, as the data did not rigorously follow the test of normality, the Kruskal–Wallis test was used to compare the differences among the groups, followed by the Dunn–Bonferroni adjusted post-hoc test. Non-remitted MDD patients and BD patients, regardless of remission/non-remission, presented more severe ERPD than healthy subjects. This study also demonstrated the relationships between all anxiety-related symptoms, including social phobia and anxious-depressive attack and ERPD, in both BD and MDD patients and in healthy subjects. In conclusion, patients with non-remitted MDD and with BD regardless of remission/non-remission experience severe ERPD related to anxiety-related symptoms.

show abstract

Distinctive Clinical Features of “Anxious-Depressive Attack”

Abstract: Background: Anxious-depressive attack (ADA) is a proposed novel symptom complex associated with

Cited by 10 publications

References 17 publications

Effects of Rejection Sensitivity on the Development of Anxious-Depressive Attack in Patients with Social Anxiety Disorder

Effects of Rejection Sensitivity on the Development of Anxious-Depressive Attack in Patients with Social Anxiety Disorder

Anxious‐depressive attack and rejection sensitivity—Toward a new approach to treatment‐resistant depression

Evaluating psychological distress associated with life events under the traumatic experience threshold in patients with major depressive and bipolar disorder

Contact Info

Product

Resources

About