Distinctive features of idiopathic inflammatory myopathies inFrench Canadians

Uthman, Imad; Vázquez‐Abad, Dolores; Senécal, Jean‐Luc

doi:10.1016/s0049-0172(96)80025-4

Cited by 42 publications

(38 citation statements)

References 31 publications

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“…Raynaud's phenomenon was not often reported by the patients, and its frequency was not statistically different between DM and PM or between sexes as in other works 17,19 . Fever was statistically more frequently presented by patients with mild-early DM than by those with definite DM, and this aspect corroborates the consulted literature, which refers fever to be one of the commonest initial manifestations of dermatomyositis 3 .…”

Section: Fig 4 Transverse Section Of a Fresh-frozen Muscle Biopsy Spsupporting

confidence: 52%

“…The present study evidences that myalgia is an important symptom in reinforcing the diagnosis, however it is unable to determine it. Table 5 shows the comparison of the demographic data, clinical presentations and laboratory features between our study and others 17,[19][20][21][22][23][24] .…”

Section: Fig 3 Transverse Section Of a Fresh-frozen Muscle Biopsy Spmentioning

confidence: 99%

“…The term overlap syndrome is often used to indicate that the characteristics of two different disorders are common to both. Many studies have shown that only dermatomyositis, and not polymyositis, truly overlaps in up to 20 percent of patients, with connectivetissue diseases, and only with systemic sclerosis and mixed connective tissue disease 3,16,19,25 . However, there is a study showing 19 patients with PM and 2 patients with DM in overlap with other CTD among 177 patients 26 .…”

Section: Fig 4 Transverse Section Of a Fresh-frozen Muscle Biopsy Spmentioning

confidence: 99%

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Diagnosis of dermatomyositis and polymyositis: a study of 102 cases

Scola

Werneck

Prevedello³

et al. 2000

Arq. Neuro-Psiquiatr.

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-Patients with dermatomyositis (DM) or polymyositis (PM) were studied retrospectively. The patients were divided into four groups: definite PM 24, probable PM 19, definite DM 34 and mild-early DM 25 cases. PM patients complained more often proximal muscle weakness [p <0.01 -inicial [p<0,03]. Conclusão: Foi encontrada baixa frequência de associação com colagenoses e neoplasias. DM e PM são clinicamente diferentes. A DM apresenta envolvimento sistêmico afetando a pele, desenvolvendo quadro mais severo de artralgia, disfagia, perda de peso e gerando valores mais elevados de VHS. A PM apresenta um acometimento restrito e mais importante da musculatura ocasionando maiores queixas de fraqueza e mais altos níveis séricos das enzimas musculares. PALAVRAS-CHAVE: polimiosite, dermatomiosite, miopatia inflamatória, diagnóstico.

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Section: Fig 4 Transverse Section Of a Fresh-frozen Muscle Biopsy Spsupporting

confidence: 52%

Section: Fig 3 Transverse Section Of a Fresh-frozen Muscle Biopsy Spmentioning

confidence: 99%

Section: Fig 4 Transverse Section Of a Fresh-frozen Muscle Biopsy Spmentioning

confidence: 99%

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Diagnosis of dermatomyositis and polymyositis: a study of 102 cases

Scola

Werneck

Prevedello³

et al. 2000

Arq. Neuro-Psiquiatr.

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“…The calculated annual incidence rate for PM/DM is 5.18 cases per million populations per year; this is consistent with the reported rates in developed countries [1][2][3][4]. Our patients presented with similar clinical features in the reported series [5,8,9].…”

Section: Discussionsupporting

confidence: 91%

Polymyositis and dermatomyositis in Sarawak: a profile of patients treated in the Sarawak general hospital

Teh¹,

Wong²,

Soo³

2011

Rheumatol Int

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We performed a cross-sectional study of the demography, clinical and laboratory features of patients with polymyositis and dermatomyositis followed up in our centre from 2006 to 2009. There were 12 cases, with the majority of them (58.3%) being woman. They have a mean age of 57.8 years and mean disease duration of 11.83 (SD 9.92) months. Our patients comprised of multi-ethnic groups with predominantly Chinese (83.3%), Sarawak natives (8.3%) and Malays (8.3%). They have a mean lag time to diagnosis of 3.67 (SD 4.27) months. Nine (75%) patients had dermatomyositis and 3(25%) had polymyositis. The common clinical manifestations found in our patients were proximal myopathy (100%), neck weakness (33.3%), dysphagia (33.3%) and interstitial lung disease (33.3%). For the nine patients with dermatomyositis, the most common dermatological manifestations were shawl sign (88.9%) and V sign (88.9%). Muscle enzymes were raised in 91.7% of patients. Electromyographies were carried out in four patients, and only one of our patients had muscle biopsy. Only 41.7% of our patients have positive ANA. The majority received prednisolone (100%) and hydroxychloroquine (58.3%). Malignancy occurred in five (three nasopharyngeal carcinomas, one sigmoid colon cancer and one lung cancer) out of the nine dermatomyositis patients but none in the polymyositis group. The mortality rate in our group was 4(33.3%) over the 4-year period. This study demonstrated the rarity of PM/DM in our centre with considerable lag time to diagnosis in our patients. Despite lack of muscle biopsy in our centre, our centre achieved appropriate diagnosis and management of PM/DM.

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“…The prevalence of skin rashes in SLE while myositis and muscle weakness was presented in MCTD was expected since these are typical clinical manifestation associated with each of these autoimmune illnesses (Uthman et al, 1996;Belibou et al, 2012;Szodoray et al, 2012). Like others (Watanabe et al, 2012;Gunnarsson et al, 2013;Zidan et al, 2013), the data showed that specific organ malfunction was involved with each of these syndromes where renal disease was elevated in SLE cohort while myocardial infarction was more frequently in the MCTD population (p ≤ 0.002).…”

Section: Discussionmentioning

confidence: 80%

Auto-antigenic Properties of the Spliceosome as a Molecular Tool for Diagnosing Systemic Lupus Erythematosus and Mixed Connective Tissue Disease Patients

Mesa¹

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Distinctive features of idiopathic inflammatory myopathies inFrench Canadians

Cited by 42 publications

References 31 publications

Diagnosis of dermatomyositis and polymyositis: a study of 102 cases

Diagnosis of dermatomyositis and polymyositis: a study of 102 cases

Polymyositis and dermatomyositis in Sarawak: a profile of patients treated in the Sarawak general hospital

Auto-antigenic Properties of the Spliceosome as a Molecular Tool for Diagnosing Systemic Lupus Erythematosus and Mixed Connective Tissue Disease Patients

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