Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people

Genetic history of esophageal cancer group in southwestern China revealed by Y‐chromosome STRs and genomic evolutionary connection analysis

“…Sichuan is situated in southwestern China and is surrounded by mountains, which historically made transportation difficult and created natural geographic isolation. Due to wars and disasters, Sichuan has experienced extreme population loss [ 72 ]. To restore economic and social order in Sichuan, the government has implemented a series of policies to encourage migrants from different parts of the country to move into Sichuan and rebuild their homes.…”

Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource

“…In addition, to explore the genetic relationship between TK people and other modern and ancient eastern Eurasians, we merged our genome-wide data with previously published modern and ancient people from the Allen Ancient DNA Resource (AADR), which formed a low-density merged HO dataset [ 28 , 29 ], including 56,814 SNPs, and a middle-density merged 1240K dataset, including 146,802 SNPs. To explore the fine-scale genetic structure and obtain phased genomes to illuminate the biological adaptation mechanisms, we combined our data with previously published Illumina data [ [49] , [50] , [51] , [52] , [53] , [54] , [55] , 62 ], 54 worldwide populations included in the HGDP [ 28 ], and 20 populations from Taiwan Island, SEA Island, and Oceania included in the Oceanian genomic resources [ 29 ], which formed the high-density merged WGS dataset and included 460,678 SNPs.…”

Population genetic admixture and evolutionary history in the Shandong Peninsula inferred from integrative modern and ancient genomic resources

“…Recent studies utilizing ancient genomic resources have revealed that human expansion from regions such as the Mongolia Plateau, Amur River Basin, Yellow River Basin, Yangtze River Basin, and the Eurasian Steppe has gradually facilitated complex patterns of population structure and genetic diversity in East Asia [ 5 – 8 ]. Evolutionary reconstructions among ethnolinguistically modern populations suggest that differentiated selective pressures and admixture landscapes have enriched the complexity of the population history and biological adaptations of East Asians [ 6 , 9 – 12 ]. Yang et al identified genomic substructures between ancient northern East Asians (ANEAs) and ancient southern East Asians (ASEAs).…”