Distinguishing Untreated Osteoblastic Metastases From Enostoses Using CT Attenuation Measurements

Ulano, Adam; Bredella, Miriam A.; Burke, Patrick S.; Chebib, Ivan; Simeone, F. A.; Huang, Ambrose J.; Torriani, Martin; Chang, Connie Y.

doi:10.2214/ajr.15.15559

Cited by 89 publications

(44 citation statements)

References 28 publications

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“…Meticulous and specific CT attenuation is required to better diagnose or differentiate these lesions from osteoblastic metastasis as described in a study comprising large series [13]. The study highlights importance of specific attenuation thresholds in order to differentiate osteosclerotic islands from untreated osteoblastic metastatic lesions.…”

Section: A B Cmentioning

confidence: 94%

Bone island and hand involvement - A short review

Dharmshaktu¹,

Singh²

2018

Hand Microsurg

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Bone island or enostosis is an enigmatic lesion affecting the skeleton system. As these anomalies have limited clinical implications owing to an asymptomatic course with most cases diagnosed incidentally, the exact etiopathogenesis is not clearly understood. A lot has been studied regarding radiological features and morphology despite scarce clinical cases and relevant studies. More research is warranted to provide in-depth details of these lesions that has potential to enlighten us with newer aspects of bone metabolism and properties. These lesions might just not be an aberration and may offer important clues about bone behavior and morphogenesis. Bone islands, when in large number, are associated with equally fascinating disorder called osteopoikilosis. This review, however, does not include osteopoikilosis on purpose. Hand involvement, although rarer, has been described and a short review is attempted to acknowledge that apart from relevant facts on diagnosis and management.

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Section: A B Cmentioning

confidence: 94%

Bone island and hand involvement - A short review

Dharmshaktu¹,

Singh²

2018

Hand Microsurg

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“…50,52 Bone islands are much more common than sclerotic metastases and tend to have higher bone density. 53,54 This density difference can be used to distinguish bone island and sclerotic metastasis with a high level of certainty. This is done by drawing a region of interest (ROI) as large as possible on the lesion without extending beyond the lesion's margins, irrespective of whether intravenous contrast was administered or not.…”

Section: Bone Mineral Densitymentioning

confidence: 99%

Advanced Quantitative Spine Imaging

Griffith¹

2020

Semin Musculoskelet Radiol

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Although advanced quantitative imaging may not be currently used to any degree in the routine reporting of spinal examinations, this situation will change in the not too distant future. Advanced quantitative imaging has already allowed us to understand a great deal more regarding spinal development, marrow physiology, and disease pathogenesis. Radiologists are ideally suited to drive this research forward. To speed up this process and optimize the impact of studies reporting spine quantitative data, we should work toward universal standards on the acquisition of spine data that will allow quantitative studies to be more easily compared, contrasted, and amalgamated.

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“…They can be differentiated from other sclerotic lesions like untreated metastases on CT because their mean Hounsfield unit is > 885. 27 Myositis ossificans (heterotopic ossification) is relatively common around the hip and gluteal muscles, and it may mimic a bone tumor. MRI appearance relates to age of the lesion but may show reactive soft tissue and intraosseous abnormalities (most common when the patient presents with symptoms) that are important features in distinguishing myositis ossificans from sarcoma.…”

Section: Langerhans Cell Histiocytosismentioning

confidence: 99%

“…Metastases are usually less homogeneous, may have a rim of edema (halo sign), and a mean attenuation on CT < 885 HU. 27 Learning point: In adults, most metastases arise from lung (lytic or mixed), kidney (lytic), breast (blastic or mixed), prostate (blastic), colon (mixed), bladder (lytic or mixed), and thyroid (lytic) primaries. In children, bone metastases may occur with neuroblastoma (particularly in children < 2 years), rhabdomyosarcoma, osteosarcoma, ES, teratoma, and Wilms' tumors.…”

Section: Malignant Tumors In the Hip And Pelvismentioning

confidence: 99%

Hip and Pelvis Bone Tumors: Can You Make It Simple?

Afonso

Weber

Isaac

et al. 2019

Semin Musculoskelet Radiol

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Although it is possible for any osseous tumor or tumorlike lesion to occur in and around the hip and pelvis, there are preferential lesions. Most tumors share many imaging features with those arising elsewhere in the skeletal system, but some may show specific morphological and imaging features. Furthermore, specific criteria and rules of thumb are related to this anatomical area that radiologists should know, which together with the imaging findings and clinical context will lead to a more confident diagnosis.In this article we review the basic anatomical and imaging principles in the hip and pelvis and their diagnostic criteria, describe the most common regional benign and malignant bone tumors and pseudotumors, and highlight their main imaging features and common differential diagnosis while keep this article as relatively simple and straightforward as possible. Soft tissue tumors are beyond the scope of this article.

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Distinguishing Untreated Osteoblastic Metastases From Enostoses Using CT Attenuation Measurements

Abstract: CT attenuation measurements can be used to distinguish untreated osteoblastic metastases from enostoses. A mean attenuation of 885 HU and a maximum attenuation of 1060 HU provide reliable thresholds below which a metastatic lesion is the favored diagnosis.

Cited by 89 publications

References 28 publications

Bone island and hand involvement - A short review

Bone island and hand involvement - A short review

Advanced Quantitative Spine Imaging

Hip and Pelvis Bone Tumors: Can You Make It Simple?

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