“…High-frequency tone-burst-evoked ABR have been found to be even more useful in identifying early ototoxicity changes [36,37]. A number of researchers have found DPOAE, a specific measure of OHC activity, a particularly useful and more easily administered modality to monitor for early cisplatin otoxicity [38][39][40]. As seen in this case (Fig.…”
“…High-frequency tone-burst-evoked ABR have been found to be even more useful in identifying early ototoxicity changes [36,37]. A number of researchers have found DPOAE, a specific measure of OHC activity, a particularly useful and more easily administered modality to monitor for early cisplatin otoxicity [38][39][40]. As seen in this case (Fig.…”
“…In a number of studies focusing on ototoxicity in children, otoacoustic emissions were applied for monitoring ototoxicity . Currently, otoacoustic emissions are widely used in newborn hearing screening programs and are validated by professional organizations as a reliable and objective tool …”
The wide range of SNHL incidence rates makes it impossible to draw any conclusions on the severity of RT- and CRT-induced ototoxicity. To allow for future comparison of study outcomes, development of uniform criteria is of utmost importance.
“…Distortion product otoacoustic levels, as a function of frequency, were elicited by the use of two simultaneous pure‐tone stimuli at different frequencies, f1 and f2 (where f1 < f2 and f1/f2 = 1.2), between 1 and 8 kHz. The stimulus intensity was 65 dB for f1 and 55 dB for f2, as recommended by Chida et al10 A difference of 4 dB SPL for DPOAEs was used as a cutoff point 11…”
For complex lateral mandibular defects (≤6 cm), a combination of the pedicled mandible myo-osseous flaps and free skin flaps is an alternative in reconstruction.
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