Distraction Osteogenesis in the Irradiated Canine Mandible

Treatment of primary malignant bone tumours of the distal tibia

“…In one case, the bone transport became infected and was later followed by an amputation. The resected limb had been irradiated post-operatively, and bone transport in irradiated bones is a controversial issue [7,10]; our experience does not support this procedure. Bone transport is a demanding procedure in which many problems may occur.…”

Biomechanical Configurations of Mandibular Transport Distraction Osteogenesis Devices

“…This technique of skeletal regeneration generally involves four stages 1,2 : (1) creation of a full osteotomy or a corticotomy, (2) latency period or callus formation between two bone ends, (3) distraction period or bone formation by callus stretching, and (4) consolidation or new bone tissue maturation. Although distraction osteogenesis was first popularized by Ilizarov in the mid-20th century to correct long bone defects, 3,4 its application was extended to the distraction of the membranous bones of the craniofacial skeleton by Snyder et al in 1973.…”

“Transport Distraction Osteogenesis for Reconstruction of Mandibular Defects”: Our Experience

“…Other animal studies have shown that the diameter of the regenerated bone is comparable to pre existing bone. Gantous et al [14] demonstrated that distraction osteogenesis was feasible even in previously radiated mandible. Annino et al successfully applied trifocal distraction to bridge the defect by moving two transport segments towards each other in dogs.…”

“…Synthetic materials generally retain the characteristics of a foreign body and fail to fully replace living tissues in appearance or function. Distraction osteogenesis has been proposed as an alternate method of reconstruction, through which mandibular defects could be replaced by new bone grown from the remaining mandible [14].…”