Distress in neurocognitive disorders due to Alzheimer's disease and stroke

Abstract

Patients with neurocognitive disorders experience subjectively the concept of quality of life; this is the reason why researchers avoid approaching this concept and prefer to focus attention on the emotional profile of the caregivers. Many studies highlight the efforts both emotional and financial made by caregivers in case of patients diagnosed with neurocognitive disorders. The present study shows the differences between the patients diagnosed with neurocognitive disorder due to Alzheimer's disease and patients diagnosed with stroke, as well as the Romanian norms for the short form of Geriatric Depression Scale. The study group consisted of the clinical population (N=45), selected according to the inclusion/exclusion criteria, following the principles of Helsinki Declaration for Ethical Medical Research.

Elucidating the Effects of a Cryptomeria fortunei Forest Environment on Overall Health Based on Open Field Testing of Mice

“…However, the exact pathogenesis is still elusive. In recent years, many theories have been proposed, including the monoamine theory, dysfunction in hypothalamus-pituitary-adrenal (HPA) axis hypothesis, and neurotrophic theory inflammatory theory [64][65][66][67]. Studies demonstrated that immune system activation played a major role in the development of depression [68,69].…”

A Comprehensive Machine Learning Framework for the Exact Prediction of the Age of Onset in Familial and Sporadic Alzheimer’s Disease

“…While AD cannot be cured and there is no way to stop or slow its progression at the moment, our approach offers the possibility of treating symptoms several years before they begin to appear [ 4 , 99 , 100 ] under an individually tailored biomarker scheme rather, than using a one-size-fits-all population average strategy [ 99 , 100 , 101 ], while taking individual variability into account. Although our results can certainly be used to move AD research in this direction, it is also important to consider the legal implications and the preparation that health providers, neurologists, and centers specializing in AD and neurodegeneration must have in order to interpret these findings and provide proper counseling to patients and their families [ 102 , 103 , 104 ]. Another challenge in the years to come is also to significantly reduce the misinformed conclusions produced by ML methods in the absence of clinical domain expertise [ 105 ].…”

Effects of Anti-Inflammatory Treatment and Surgical Intervention on Endothelial Glycocalyx, Peripheral and Coronary Microcirculatory Function and Myocardial Deformation in Inflammatory Bowel Disease Patients: A Two-Arms Two-Stage Clinical Trial

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