Distribución demográfica y prevalencia de la vejiga hiperactiva en Venezuela

Dávila, H.; López, V.; Nieves, L.; Colantuono, Aline Correia de Sousa; Guaiquirián, L.; Sánchez, P.; Acosta, F; Mack, S.; Marcano, N.; Martínez, Carlos de Ayala; Toro, J. Rioja; Moreira, Osvaldo Costa; Hernández, María Luisa García; Kański, Andrzej; Delgado, J.; Sánchez-Salas, Rafael

doi:10.1016/s0210-4806(10)70036-x

Cited by 6 publications

(3 citation statements)

References 20 publications

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“…We observed a probable OAB diagnosis in more than half of women using the OAB-V8 questionnaire. Davila et al ( 24 ) reported similar results (51%) using the same questionnaire, and also questioned the reliability of isolated use of this instrument for OAB diagnosis. Thus, if we consider only the OAB-V8 questionnaire our outcomes may be overestimated.…”

Section: Discussionmentioning

confidence: 82%

Schooling impacts on the overactive bladder diagnosis in women

et al. 2017

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Objective:To evaluate the overactive bladder (OAB) diagnosis using OAB-V8 and ICIQOAB questionnaires in women with different schooling and cultural levels.Materials and Methods:Three hundred and eighty six healthy women answered a clinical questionnaire filling out information about schooling, demographic and gynecological data. The OAB-V8 and ICIQ-OAB questionnaires were used to evaluate OAB diagnosis and symptoms; and the QS-F questionnaire, to determine the sexual function. All questionnaires were validated in Portuguese.Results:The mean age was 37.3 years-old. Regarding to schooling level, 23.1% had concluded primary education; 65.8%, secondary school; and 11.1% had higher education. Considering the OAB-V8 (score ≥8), 51.8% of evaluated women had OAB diagnosis. There was a positive linear correlation between the OAB-V8 and ICIQ-OAB questionnaires in its sections “a” (r=0.812, p<0.001) and “b” (r=759, p<0.001). There was a positive linear correlation between age and the amount of time used to answer the OAB-V8, ICIQ-OAB and QS-F questionnaires (p<0.001).The ICIQ-OAB was the hardest to answer for all schooling levels when compared to the other questionnaires. Women who had concluded primary and secondary education significantly demanded more help to answer all questionnaires than those with higher education (p<0.05). Furthermore, women with higher education took significantly less time answering all questionnaires when compared to their less educated counterparts (primary and secondary schooling), since they were quicker to answer each individual question.Conclusion:Educational level and ageing had an impact on women response using different questionnaires for OAB and sexual function evaluations.

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Section: Discussionmentioning

confidence: 82%

Schooling impacts on the overactive bladder diagnosis in women

et al. 2017

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“…In 2010, a multicentric assessment using the OAB-V8 questionnaire was conducted in Venezuela in a total of 3,407 18-75 year-old adults, with 38% of them being males. The prevalence of overactive bladder in this population was 21% ( 8 ). Other studies conducted in Latin America found a similar prevalence; 23.4% and 18.9%, in Argentina and Brazil, respectively ( 9 , 10 ).…”

Section: Introductionmentioning

confidence: 82%

“…In Finland, its prevalence in women was 9.3% and 6.5% in men ( 6 ). In Venezuela, the study revealed that women were more often affected than men – 25.6% and 13.7%, respectively ( 8 ). The same result was observed by Teloken et al, in Brazil, where the condition was reported by 23.3% of women and 14% of men ( 10 ), as well as Temml et al, with 16.8% of women and 10.2% of men reporting it ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Overactive bladder – 18 years – part I

et al. 2016

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Overactive bladder syndrome is one of the lower urinary tract dysfunctions with the highest number of scientific publications over the past two decades. This shows the growing interest in better understanding this syndrome, which gathers symptoms of urinary urgency and increased daytime and nighttime voiding frequency, with or without urinary incontinence and results in a negative impact on the quality of life of approximately one out of six individuals – including both genders and almost all age groups. The possibility of establishing the diagnosis just from clinical data made patients' access to specialized care easier. Physiotherapy resources have been incorporated into the urological daily practice. A number of more selective antimuscarinic drugs with consequent lower adverse event rates were released. Recently, a new class of oral drugs, beta-adrenergic agonists has become part of the armamentarium for Overactive Bladder. Botulinum toxin injections in the bladder and sacral neuromodulation are routine modalities of treatment for refractory cases. During the 1st Latin-American Consultation on Overactive Bladder, a comprehensive review of the literature related to the evolution of the concept, epidemiology, diagnosis, and management was conducted. This text corresponds to the first part of the review Overactive Bladder 18-years.

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Cost Effectiveness of Mirabegron Compared with Antimuscarinic Agents for the Treatment of Adults with Overactive Bladder in Colombia

Parisé¹,

Espinosa²,

Dea³

et al. 2019

PharmacoEconomics Open

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Objectives The aim of this study was to evaluate the cost effectiveness of mirabegron relative to two antimuscarinics, oxybutynin extended release (ER) and tolterodine ER, in patients with overactive bladder (OAB) from the perspective of a third-party payer in Colombia. Methods A Markov model simulated the therapeutic management, disease course, and complications in hypothetical cohorts of OAB patients over a 5-year period. The model predicted costs and three outcomes: quality-adjusted life-years (QALYs), micturition state improvement (MSI), and incontinence state improvement (ISI). In each 1-month cycle, patients could transition between different health states reflecting symptom severity. Transition probabilities were estimated from a published mirabegron trial and mixed treatment comparison. Other inputs such as treatment discontinuation based on treatment-specific rates of persistence, resource use and costs, anticholinergic burden, comorbidity treatment, and drug acquisition were obtained from Società Italiana Scienze Mediche, Instituto de Seguros Sociales Tariff Manual, published literature, and expert opinion. Deterministic and probabilistic sensitivity analyses were conducted. Costs are presented in 2017 Colombia Pesos (COP). Results Mirabegron was cost effective for all outcome measures at a willingness-to-pay threshold of 124,919,725 COP, which is three times the per capita gross domestic product (GDP). Using QALYs as the measure of effect, mirabegron had an incremental cost-effectiveness ratio (ICER) of 85,802,036 COP/QALY (26,365 USD/QALY) and 66,360,134 COP/ QALY (20,384 USD/QALY) versus oxybutynin and tolterodine, respectively. Probabilistic sensitivity analyses showed that mirabegron was cost effective in 99.5% and 100% of simulations compared with oxybutynin and tolterodine, respectively. Using MSI and ISI as the measure of effects yielded ICERs below one GDP. Conclusions Mirabegron is a cost effective alternative to oxybutynin and tolterodine from the perspective of a third-party payer in Colombia.

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Distribución demográfica y prevalencia de la vejiga hiperactiva en Venezuela

Abstract: The OAB-V8 questionnaire aids to clearly identify patients with OAB symptoms. The overall prevalence of OAB in Venezuela is 21%. It is present in both genders, predominantly women and can be detected at early age.

Cited by 6 publications

References 20 publications

Schooling impacts on the overactive bladder diagnosis in women

Schooling impacts on the overactive bladder diagnosis in women

Overactive bladder – 18 years – part I

Cost Effectiveness of Mirabegron Compared with Antimuscarinic Agents for the Treatment of Adults with Overactive Bladder in Colombia

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