Distribution and identity of phytoecdysteroids in Gomphrena spp. (Amaranthaceae)

Savchenko, Tamara; Whiting, Pensri; Sarker, Satyajit D.; Dinan, Laurence

doi:10.1016/s0305-1978(97)00106-3

Cited by 11 publications

(5 citation statements)

References 14 publications

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“…A recent study showed that quinoa seed leachate containing 20HE inhibited matrix metalloproteinase (MPP) activity and production of intracellular ROS . No data is available for amaranth seed, however, Gomphrena haageana , a plant that belongs to the same family as quinoa and amaranth contained as high as 2580 mg/kg seed . Although 20HE is ingredient of some nutritional supplements for several physiological benefits, most of its human health benefits are yet to be validated, and further studies are necessary, especially for the effect of quinoa and amaranth on the prevention and treatment of diabetes, obesity and the associated disorders.…”

Section: Main Bioactive Components In Quinoa and Amaranth Seedsmentioning

confidence: 99%

Phytochemicals in quinoa and amaranth grains and their antioxidant, anti‐inflammatory, and potential health beneficial effects: a review

Tang

Tsao

2017

Molecular Nutrition Food Res

258

168

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Quinoa (Chenopodium quinoa Willd.) and amaranth (Amaranthus cruentus L.) are pseudocereal grains rich in both macronutrients and micronutrients including vitamins and minerals. The proteins are particularly of high nutritional quality due to the outstanding balance of essential amino acids. However, recent research strongly suggests that nonessential nutrients such as phytochemicals of quinoa and amaranth may also have potential health beneficial effects. This review focuses on the phytochemical composition of quinoa and amaranth seeds, the antioxidant and anti-inflammatory activities of hydrophilic (e.g. phenolics, betacyanins) and lipophilic (e.g. fatty acids, tocopherols, and carotenoids) nutrients, and how these contribute to the potential health benefits, especially in lowering the risk of the oxidative stress related diseases e.g. cancer, cardiovascular disease, diabetes, and obesity. The gap between current knowledge and future research needs have also been identified.

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Section: Main Bioactive Components In Quinoa and Amaranth Seedsmentioning

confidence: 99%

Phytochemicals in quinoa and amaranth grains and their antioxidant, anti‐inflammatory, and potential health beneficial effects: a review

Tang

Tsao

2017

Molecular Nutrition Food Res

258

168

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“…Phytochemical studies with in the genera Amaranthus account for the presence of saponins (Takemoto et al, 1983;Nishimoto et al, 1984;Oleszek et al, 1999), sapogenins (Escudero et al, 1998), rutin (Xaziev et al, 1992), steroids (Ologunde et al, 1992) and hydroxycinnamic esters of isocitric acid (Strack et al, 1987). Several works describe the antitumor activity of the genera Gomphrena, possibly associated to the production of saponins and phytoecdisteroids (Pomilio et al, 1994;Sarker et al, 1996;Young et al, 1997;Savchenko et al, 1998). Gomphrena elegans Mart.…”

Section: In Vitro Cytotoxic Activity Of Brazilian Middle West Plant Ementioning

confidence: 99%

In vitro cytotoxic activity of Brazilian Middle West plant extracts

Mahmoud¹,

Marques²,

Pessoa³

et al. 2011

Rev. bras. farmacogn.

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Cytotoxic activity of eight plant extracts, native from the MidWest of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL -1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL -1 ) was used as the positive control and the MTT method was used to detect the activity. Cytotoxicity of distinct polarities was observed in thirty extracts (46%), from different parts of the following species: Tabebuia heptaphylla (Vell.) Toledo, Bignoniaceae, Tapirira guianensis Aubl., Anacardiaceae, Myracrodruon urundeuva Allemão, Anacardiaceae, Schinus terebinthifolius Raddi, Anacardiaceae, Gomphrena elegans Mart., Amaranthaceae, Attalea phalerata Mart. ex Spreng., Arecaceae, Eugenia uniflora L., Myrtaceae, and Annona dioica A. St.-Hil., Annonaceae. Extracts of at least two tested cell strains were considered to be highly active since their inhibition rate was over 75%.

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“…The analytical strategy described above is generally applicable for the assessment of ecdysteroids in plant samples. The principles have been described as applied to a limited number of species in the genus Sida, but the approach has been extended to species in genera such as Atriplex, Chenopodium (Chenopodiaceae: Dinan et al, 1998), Centaurea (Compositae: Sarker et al, 1997a), Pulsatilla and Anemone (Ranunculaceae: Sarker et al, 1997b;Savchenko et al, 1998a), Gomphrena (Amaranthaceae: Savchenko et al, 1998b), Limonium (Plumbaginaceae: Whiting et al, 1998), Briza and other genera of the Gramineae (Dinan, 1995;Savchenko et al, 1998c) and Silene (Caryophyllaceae: Savchenko, Whiting and Dinan, unpublished).…”

Section: Chemotaxonomic Valuementioning

confidence: 99%

Phytoecdysteroid profiles in seeds of Sida spp. (Malvaceae)

Dinan¹,

Bourne²,

Whiting³

2001

Phytochemical Analysis

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Procedures are presented for the assessment of the phytoecdysteroid profiles in small plant samples (ca. 25 mg), using seeds of Sida spp. as an example. The procedures are suitable for the analysis of minute or valuable samples and provide copious information for chemotaxonomic purposes. Methanolic extracts of the plant material, after partitioning against hexane, were separated by reversed-phase gradient HPLC monitored by PAD, RIA and bioassay. Aliquots of the fractions were also treated with Helix pomatia hydrolases, followed by RIA and bioassay, in order to assess the presence of hydrolysable ecdysteroid conjugates. Further information could also be obtained by separation of samples using normal-phase gradient HPLC. Among 11 species of Sida examined, seed extracts of S. acuta (= S. carpinifolia) and S. rhombifolia were found to contain significant amounts of ecdysteroids, seed extracts of S. filicaulis contained only moderate levels, whilst the remaining species showed no detectable levels of ecdysteroids. The ecdysteroid profiles of the extracts of the three positive species were significantly different, demonstrating that phytoecdysteroids have chemotaxonomic value in this genus.

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Distribution and identity of phytoecdysteroids in Gomphrena spp. (Amaranthaceae)

Cited by 11 publications

References 14 publications

Phytochemicals in quinoa and amaranth grains and their antioxidant, anti‐inflammatory, and potential health beneficial effects: a review

Phytochemicals in quinoa and amaranth grains and their antioxidant, anti‐inflammatory, and potential health beneficial effects: a review

In vitro cytotoxic activity of Brazilian Middle West plant extracts

Phytoecdysteroid profiles in seeds of Sida spp. (Malvaceae)

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