Distribution and ontogeny of gastrin- and serotonin-immunoreactive cells in the proventriculus of developing chick, Gallus gallus domestica

Abstract

The ontogeny and distribution of gastrin- and serotonin-immunoreactive (IR) cell in the proventriculus of chicks (Gallus gallus domestica, n = 60) in different growth periods was examined immunohistochemically using antisera specific to gastrin and serotonin. Gastrin and serotonin-IR cells were detected in chick proventriculus. Gastrin-IR cells were first evident after 12 days of incubation in lamina epithelialis and compound glands, while serotonin-IR cells were observed only in compound glands at that same time. Gastrin-IR and serotonin-IR cells increased in frequency on incubation day 14 and 16, respectively. Towards the end of incubation, gastrin- and serotonin-IR cell numbers decreased. In adult chicken, both IR cells were present but not lower numbers. The observations demonstrate the presence of gastrin- and serotonin-IR cells in the proventriculus of developing chicks in temporally changing frequencies.

The Distribution of Gastrin, Somatostatin and Glucagon Immunoreactive (IR) Cells in Ostrich Stomach During the Pre- and Post-hatching Period

“…It is known that in the chicks of Gallus domesticus, gastrin IR cells are one of the first to appear in the pylorus mucosa: already on day 12 of incubation, but 2 days later, they are also found in the mucosa of the small intestine (Alison, ; Aksoy and Cinar, ).…”

“…() have described the main endocrine cells in the mucosa of digestive tract in adult ostriches. More detailed studies are available on immunoreactive cells of the gastrointestinal tract of other domestic fowl species (Rawdon, ; Alison, , ; Yamanaka et al., ; Rawdon and Andrew, ; Aksoy and Cinar, ).…”

“…It is known that in birds, gastrin stimulates both hydrochloric acid and pepsin secretion (Dimaline et al., ; Dimaline and Lee, ; Campbell et al., ; Rawdon and Andrew, ), and in chicken embryos, gastrin IR cells (G cells) have been found starting from the 12th (Aksoy and Cinar, )‐16th (Rawdon and Andrew, ) day of incubation in the pyloric part of the stomach.…”

Biology of the Gastrointestinal Tract in Poultry

“…Gastrin immuno-reactive cells have been reported in the chicken proventriculus (Rawdon and Andrew, 1999;Martinez et al, 1993a). The numbers of these gastrin cells are increasing during late embryonic development (Aksoy and Cinar, 2009).…”

“…There is strong parasympathetic innervation of the proventriculus by two networks, respectively the myenteric and submucous plexus (Martínez et al, 2000). Both gastrin and serotonin containing presumptive endocrine cells are found in the proventriculus with these especially abundant in late embryonic development (chicken: Aksoy and Cinar, 2009).…”