Distribution and Structural Organization of the Autonomic Nervous Apparatus in the Rat Pancreas (an immunohistochemical study)

Ei, Chumasov; Петрова, Е. С.; Коржевский, Д. Э.

doi:10.1007/s11055-012-9635-6

Cited by 5 publications

(6 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was also different from those recorded in pancreatic ducts of other species such as the rabbit in which the main duct possess simple columnar epithelium with goblet cells. The presence of autonomic ganglia inside and outside pancreatic tissue was also documented recently in the pancreas of the rats 23 . These ganglia were detected as a group of cells between acini of the parenchymal tissue and interlobular connective tissue or as large ganglion adjacent to pancreatic lobule.…”

supporting

confidence: 57%

Postnatal developmental Histomorphological and histochemical study of the pancreas in the domestic cat (Felis Catus).

Saffar¹,

Zuhairy.²

2017

IJAR

View full text Add to dashboard Cite

Objective: The present study was conducted to investigate the histomorphological and histochemical postnatal developmental changes established in the pancreas of the domestic cats. Methodology: the study conducted on three different postnatal ages that were one week (suckling kittens), 4-6 weeks (weaned immature cats) and adult of one year and up cats. Macromorphometric measurements of pancreas were conducted and listed in tables. Histological sections prepared and stained by general and special stains. Results: Gross findings revealed that the pancreas of cat was of compact type, of two lobes connected by small central part. Critical macromorphometric changes observed at 4 weeks aged cats. The organ drains the pancreatic secretion toward the duodenum via main pancreatic duct. Exocrine portion more developed after birth than the endocrine portion; however both were faced developmental changes. The parenchyma provided with well duct system even in kitten. Ducts were surrounded by smooth muscle fibers invested in the connective tissue. Endocrine portion showed in kittens predominant α cells. Critical changes occurred at 4 weeks of age caused an increase of the number of ß cells so that the ratio of α / ß was changed. In adult cats the percentage of ß was predominant. In all studied ages of cats, the findings revealed the presence of well developed autonomic innervations represented by the presence of large autonomic ganglion, intramural ganglia and large sized Pacinian corpuscles. Conclusions: It could be concluded that pancreas was not fully developed at birth and weaning period caused critical development.Copy Right, IJAR, 2017,. All rights reserved. …………………………………………………………………………………………………….... Significance of the study:The significance of the current findings can be categorized into two criteria. First of all, it was first investigation focused on the development of the pancreas postnatally of the domestic cats in veterinary field. The second criteria, as the pancreas of the cats showed morphological similarities to those of human especially the presence of Pacinian ISSN: 2320-5407Int. J. Adv. Res. 5(2), 55-71 56 corpuscles, presence and distribution of α and β cells in the islets of Langerhans, such findings will be beneficial for public health and animal health and welfare.

show abstract

supporting

confidence: 57%

Postnatal developmental Histomorphological and histochemical study of the pancreas in the domestic cat (Felis Catus).

Saffar¹,

Zuhairy.²

2017

IJAR

View full text Add to dashboard Cite

show abstract

“…Four types of plexuses (perivascular, periductal, periacinar and peri-insular) have been identified in the mouse pancreas [14]. Similar data were obtained in studies on the pancreas of the rat [15] and nutria [16].…”

Section: Introductionsupporting

confidence: 71%

Neuro-Insular Complexes in the Human Pancreas

Krivova¹,

Proshchina²,

Barabanov³

et al. 2017

Challenges in Pancreatic Pathology

View full text Add to dashboard Cite

It is well known that pancreatic islets are complex structures composed of endodermally derived endocrine cells, integrated with endothelial cells and other cells, originating from the mesoderm, and innervated by nerve fibers that have a neuroectodermal origin. In our studies, we focused on the interactions between the structures of the nervous system and endocrine cells, the so-called neuro-insular complexes, in the human pancreas. In this chapter, we present our results and literature data concerning the morphological organization of neuro-insular complexes in humans and other mammals. We also discuss the possible functional role of neuro-insular complexes, such as the involvement of the nervous system in the regulation and synchronization of islet hormone secretion and the morphogenetic plasticity of the endocrine pancreas in adults, as well as in the regulation of endocrine cell proliferation and maturation during prenatal development of the pancreas.

show abstract

“…Four types of plexuses (perivascular, periductal, periacinar and peri-insular) have been Autonomic Nervous System identified in the mouse pancreas [18]. Similar data were obtained in studies on the pancreas of the rat and nutria [22,23]. One of the most interesting features of the mammalian pancreas is that endocrine cells may form highly organised complexes with structures of the nervous system, so-called neuro-insular complexes (NICs).…”

Section: Introductionsupporting

confidence: 62%

Development of Human Pancreatic Innervation

Proshchina¹,

Krivova²,

Леонова³

et al. 2018

Autonomic Nervous System

View full text Add to dashboard Cite

Human pancreatic innervation is of particular interest due to its possible role in the pathogenesis of such diseases as diabetes mellitus, pancreatitis and pancreatic cancer. Despite the clinical importance, data concerning pancreatic innervation during human ontogeny and in various disorders are very limited. In this chapter, we present a review on human pancreatic autonomic innervation on the basis of the literature data and our previous results. Special attention is paid to the innervation of the endocrine pancreas. Gradual branching of neural network was seen during human pancreatic development. Innervation of the foetal pancreas is more abundant than in adults. In agreement with previous observations, we have revealed a close integration and similarity between endocrine cells and nervous elements in the developing human pancreas. Moreover, simultaneous interactions between the nervous system components, epithelial cells and endocrine cells were detected in the pancreas during prenatal human development. It has been suggested that pancreatic innervation plays an important role not only in regulation of endocrine and exocrine activity but also in normal islet morphogenesis.

show abstract

Distribution and Structural Organization of the Autonomic Nervous Apparatus in the Rat Pancreas (an immunohistochemical study)

Cited by 5 publications

References 17 publications

Postnatal developmental Histomorphological and histochemical study of the pancreas in the domestic cat (Felis Catus).

Postnatal developmental Histomorphological and histochemical study of the pancreas in the domestic cat (Felis Catus).

Neuro-Insular Complexes in the Human Pancreas

Development of Human Pancreatic Innervation

Contact Info

Product

Resources

About