Distribution of ABO and Rh blood groups in patients with tuberculosis in Rohilkhand region of Uttar Pradesh

Abstract

among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the human immunodeficiency virus. According to latest estimates, over 8.6 million new TB cases were seen in 2012 and a whooping 1.3 million deaths due to TB in the world. The number of deaths due to TB is unacceptably large given that most are preventable. [1] Among the various factors that contribute to a person's individuality are antigens that are attached to the surface of red blood cells (RBCs) and naturally occurring antibodies that circulate in the serum. The various combinations of antigens and antibodies determine various blood groups. [2] The antigens of the ABO blood group system (A, B, and H determinants, respectively) are complex carbohydrate molecules on the extracellular surface of RBC membranes. [3] However, along with their expression on RBCs, ABO antigens Background: Tuberculosis is an infectious disease and cause of ill-health among millions of people each year. The antigens of the ABO blood group system (A, B, and H determinants, respectively) are complex carbohydrate molecules on the extracellular surface of red blood cell membranes. Several studies conducted have shown significant association between ABO blood groups of people and pulmonary tuberculosis (PTB). Objective: To determine an association between ABO blood grouping and rhesus (Rh) typing in patients with PTB (both sputum positive and negative) and extrapulmonary tuberculosis. Materials and Methods: A prospective hospital-based study was conducted among patients attending

A study to find the correlation between ABO blood group and pulmonary tuberculosis

“…In the available literature, the association between blood group and various infectious diseases such as plague, anthrax, cholera, smallpox was reported [13][14][15][16]. Similarly, blood groups and PT correlation studies are also available [4,17,18]. In a study by Rao et al, the authors reported significant association between A blood group and PT; the authors reported that among PT cases 18% PT patients were A+ and non of the participants were A- [17].…”

“…Various Factors such as quality, quantity of sputum, number of samples, staining technique used, gender and so on influence smear microscopy results [3]. Similarly, proteins present on the surface of the red blood cells (RBC) as well as the serum immunoglobulins influence the persons individuality [4].…”