Distribution of Ascorbate-2-Sulfate and Distribution, Half-Life and Turnover Rates of [1-14C]Ascorbic Acid in Rainbow Trout

Tucker, Barbee W.; Halver, John E.

doi:10.1093/jn/114.6.991

Cited by 21 publications

(10 citation statements)

References 19 publications

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“…Similar results for the appreciable or complete loss of dietary vitamin C during processing and during storage have been reported by several investigators (Hilton, Cho, Brown & Slinger 1979;Dabrowska & Dabrowski 1990;Abdelghany 1996). The greater stability of AS or APP compounds compared with the parent AA compound in fish diets has been demonstrated (Tucker & Halver 1984;Soliman, Jauncy & Roberts 1986;Grant et al 1989;El-Naggar & Lovell 1991;Abdelghany 1996).…”

Section: Discussionsupporting

confidence: 76%

Feed efficiency, nutrient retention and body composition of Nile tilapia, Oreochromis niloticus L., fed diets containing L-ascorbic acid, L-ascorbyl-2-sulphate or L-ascorbyl-2-polyphosphate

Abdelghany¹

1998

Aquaculture Res

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Seven purified diets were formulated and fed to seven groups of Nile tilapia, Oreochromis niloticus L., fingerlings for 12 weeks. Six of the formulated diets contained 5 or 50 mg kg -1 of ascorbic acid equivalent supplied by either L-ascorbic acid (AA), L-ascorbyl-2-sulphate (AS) or L-ascorbyl-2polyphosphate (APP). The seventh basal diet was ascorbate-free and served as the control. The results of diet analysis for ascorbic acid showed that it was not detected or negligible in the control diet and in the diets containing AA at the end of the experiment, whereas there was no loss of ascorbic acid from diets prepared with AS or APP. The results demonstrated that the feed efficiency and growth parameters in fish fed APP-5, AS-5, AA-5 or AA-50 diets were statistically similar to the same parameters in fish fed the control diet. The study indicated that diets supplemented with 5 or 50 mg kg -1 ascorbic acid in the form of APP or AS were more effectively utilized as sources of vitamin C than equimolar AA in promoting growth, improving food efficiency, increasing nutrient retention and preventing scurvy in Nile tilapia. Fish fed the ascorbate-free diet and the diet containing 5 mg AA kg -1 exhibited external signs of scurvy during the last growth period of the experiment. Diets containing 5 mg kg -1 of ascorbic acid from AS or APP provided some growth with no overt signs of scurvy, indicating that this concentration of AS and APP might be near the minimum requirement for the species. The APP-50 diet was the most efficient, and significantly (P Ͻ 0.05), had the lowest

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Section: Discussionsupporting

confidence: 76%

Feed efficiency, nutrient retention and body composition of Nile tilapia, Oreochromis niloticus L., fed diets containing L-ascorbic acid, L-ascorbyl-2-sulphate or L-ascorbyl-2-polyphosphate

Abdelghany¹

1998

Aquaculture Res

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“…The absence of AS in the liver of AS-or AA-fed channel catfish (Murai et al 1978) is in accordance with our findings in Atlantic salmon, suggesting that these species are not able to convert dietary AA or AS into body stores in the form of AS. Murai et al (1978) suggest cold water fishes are able to utilize AS more effectively than the warm water catfish; Tucker and Halver (1984) subsequently concurred. Our data from studies with the cold water Atlantic salmon do not confirm that such species differences exist.…”

Section: Discussionmentioning

confidence: 99%

Ascorbate-2-sulfate as a dietary vitamin C source for atlantic salmon (Salmo salar): 1. Growth, bioactivity, haematology and humoral immune response

Sandnes

Hansen²,

Killie³

et al. 1990

Fish Physiol Biochem

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The present experiment shows that ascorbate-2-sulfate (AS) is not equivalent to ascorbic acid (AA) as a dietary vitamin C source for Atlantic salmon (Salmo salar). Within reasonable feed supplemental levels AS does not provide the tissues with adequate supplies of vitamin C to secure optimal physiological functions as demonstrated by biochemical and haematological analyses.AS could not be detected in the liver of fish fed either AA or AS, nor in vitamin C - deprived salmon, suggesting that AS is not the natural storage form of vitamin C in this species.There were no significant differences in antibody production against a soluble artificial antigen (NIP11-LPH) in fish fed 500 and 5000 mg AA/Kg dry diet or equivalent amounts of AS during a period of six weeks at a water temperature of 7.2°C.

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“…I source of ascorbic acid (AA) in salmonids (1)(2)(3)(4)(5)(6). Their findings seem to run the gamut.…”

mentioning

confidence: 99%

Ascorbyl-2-Sulfate Compared with Ascorbic Acid in Atlantic Salmon: Uptake and Distribution Confirmed by Mass Spectroscopy

Felton¹,

Dukelow²,

Felton³

1997

Experimental Biology and Medicine

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This paper reports an in-depth approach that identifies ascorbyl-2-sulfate (AS) in gastric, blood, liver, and muscle tissues of Atlantic salmon (Salmo salar). To insure the identify of the AS, the study utilized the latest high-performance liquid chromatography (HPLC) technology plus electron ionization mass spectrometry (EIMS). Just before saltwater adaptation stage, juvenile Atlantic salmon were force-fed AS, ascorbic acid (AA), and a molecular-equivalent combination of the two. After tissue analyses for AA and AS were performed by HPLC separation, the HPLC peaks were identified by EIMS. The data collected in this study indicate that Atlantic salmon can absorb AS through the gastric tissue when forced-fed AA and AS as described. The data also indicate that AS is transported through the blood to the liver. There is evidence to indicate that AS is converted to AA in the livers of these salmon. In addition, the muscle tissue contained a large portion of AA and AS.

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Distribution of Ascorbate-2-Sulfate and Distribution, Half-Life and Turnover Rates of [1-14C]Ascorbic Acid in Rainbow Trout

Cited by 21 publications

References 19 publications

Feed efficiency, nutrient retention and body composition of Nile tilapia, Oreochromis niloticus L., fed diets containing L-ascorbic acid, L-ascorbyl-2-sulphate or L-ascorbyl-2-polyphosphate

Feed efficiency, nutrient retention and body composition of Nile tilapia, Oreochromis niloticus L., fed diets containing L-ascorbic acid, L-ascorbyl-2-sulphate or L-ascorbyl-2-polyphosphate

Ascorbate-2-sulfate as a dietary vitamin C source for atlantic salmon (Salmo salar): 1. Growth, bioactivity, haematology and humoral immune response

Ascorbyl-2-Sulfate Compared with Ascorbic Acid in Atlantic Salmon: Uptake and Distribution Confirmed by Mass Spectroscopy

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