Distribution of blood group and its relation to bleeding time and clotting time

Mirdha, Meena; Jena, Sunil Kumar

doi:10.5455/ijmsph.2016.13052016526

Cited by 9 publications

(11 citation statements)

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“…3,28 This discrepancy could be because the study finding only represents the result from a single hospital and may be due to inadequate samples in the Nigerian study. Many studies 3,12,15,27 conducted on epistaxis are hospital-based, but epistaxis cases are mostly self-limiting, 12 and only a few seeks medical attention; 6,7 so that the number of cases that will be presented in a health institution are rare. Contrary with the above findings, the current study showed that the level of epistaxis is lower than the studies conducted in Saudi Arabia and India, where the level of epistaxis were 49% and 45%, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Similar findings were observed in studies done in Nepal and India. 18,27 The possible reason for the observed high association may be that the O blood group is known to be associated with a lower expression of von Willebrand factor which plays an important role in clotting compared with non-O blood groups. Bleeding time is recorded to be slightly longer in blood group O.…”

mentioning

confidence: 99%

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Epistaxis and Its Associated Factors Among Precollege Students in Southern Ethiopia

Ameya¹,

Biresaw²,

Mohammed³

et al. 2021

JBM

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Epistaxis and Its Associated Factors Among Precollege Students in Southern Ethiopia

Ameya¹,

Biresaw²,

Mohammed³

et al. 2021

JBM

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“…By the comparison of bleeding time and the blood groups, those with bleeding time below and equal to 30 sec were 140 individuals that included the blood group A (26), B (57), AB (18), and O (39). Further, those who had bleeding time greater than 30 sec were 60 in numbers and the blood groups included their number were A (12), B (17), AB (7), O (24). Bleeding time and blood group had no association (p = 0.284) and were nonsignificant.…”

Section: Methodsmentioning

confidence: 98%

To check the abundance of specific ABO blood groups and its coordination with bleeding time and clotting time among individuals of different ethnicity in Quetta, Balochistan

Farzana

Taj

Ahmed

et al. 2018

PAB

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“…Hasil pengamatan menunjukkan masa aktivitas koagulasi darah kontrol (tidak diberi perlakuan) yang berkisar pada menit ke-8 hingga 12 (Tabel 3). Sampel darah kontrol yang diambil masih dalam batas waktu pembekuan darah normal, yang diketahui berkisar antara 3-18 menit (Mirdha & Jena, 2016). Sampel yang ditambah dengan ekstrak hidrolisat tidak mengalami pembekuan darah.…”

Section: Aktivitas Antikoagulanunclassified

Optimasi Hidrolisis Mikrobiologi serta Bioaktivitas Antibakteri, Antioksidan, dan Antikoagulan Hidrolisat Ulva lactuca

Putri

Hardjito

Santoso

2020

JPBKP

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Ulvan dalam hidrolisat Ulva lactuca merupakan senyawa bioaktif yang potensial di bidang biofarmakologi. Proses hidrolisis untuk memperoleh golongan senyawa ini dapat dilakukan secara kimiawi atau mikrobiologi. Proses mikrobiologi merupakan teknik yang potensial karena lebih mudah dan berbiaya rendah dibanding metode kimiawi. Namun, penelitian yang menggunakan teknik hidrolisis mikrobiologi masih sangat terbatas, terutama terhadap U. lactuca. Oleh karena itu, optimasi diperlukan agar mendapatkan teknik dengan hasil rendemen hidrolisat yang maksimal. Penelitian ini bertujuan untuk melakukan optimasi proses hidrolisis secara mikrobiologi dan menelaah aktivitas biologis ekstrak hidrolisatnya. Proses hidrolisis mikrobiologi dilakukan dengan teknik padat dan cair menggunakan kapang endofit dari tanaman Enhalus dan isolat bakteri laut dari rumput laut Eucheuma cottonii. Teknik mikrobiologis ini juga dibandingkan dengan teknik kimiawi (HCl). Optimasi dilakukan terhadap variabel durasi waktu (3, 6, 9, dan 12 hari) hidrolisis. Hasil penelitian menunjukkan bahwa rendemen metode hidrolisis cair menggunakan bantuan kapang endofit dari tanaman Enhalus (51,67%) dan isolat bakteri laut dari rumput laut E. cottonii (52,67%), lebih tinggi dan berbeda secara signifikan (p<0,05) dibandingkan teknik kimiawi (37,02%). Waktu hidrolisis terbaik yang ditemukan adalah selama tiga hari. Sementara itu, karakterisasi bioaktivitas menunjukkan bahwa hidrolisat U. lactuca memiliki potensi sebagai bahan aktif antikoagulan, tanpa adanya aktivitas sebagai antioksidan (IC50>200 ppm) maupun antibakteri (menghambat 36% Staphylococcus aureus dan Pseudomonas aeroginosa).ABSTRACTThe Ulvan in Ulva lactuca hydrolysate is a potential bioactive compound in the biopharmacology field. The hydrolysis process to obtain this class of compounds can be done in various ways, both chemically and microbiologically. The microbiological process is a potential technique because it is easier and cheaper than the chemical method. However, studies conducted with the microbiology hydrolysis technique are still very limited, especially for U. lactuca. Thus, optimation is needed to reveal an appropriate technique that produces the maximum yield. This study aimed to optimize the microbiological hydrolysis process and identify the biological activity of the hydrolyzed extract. The microbiological hydrolysis process was performed by solid and liquid techniques using microbial endophytic fungi from Enhalus plants and marine bacteria isolated from Eucheuma cottonii. The microbiology technique was compared with chemical techniques (HCl). Optimization was also carried out on the variable of hydrolysis duration (3, 6, 9, and 12 days). The results showed that yield of liquid hydrolysis method using the microbial endophytic fungi from Enhalus plants (51.67%) and marine bacteria isolated from E. cottonii (52.67%), were higher and significantly different (p<0.05) than that of chemical techniques (37.02%). Moreover, the best hydrolysis duration was found in three days. Meanwhile, bioactivity testing showed that the hydrolysate was a potent anticoagulant agent, but not prospective as antioxidant (IC50>200 ppm) or antibacterial agent (36% Staphylococcus aureus and Pseudomonas aeroginosa inhibition).

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Distribution of blood group and its relation to bleeding time and clotting time

Cited by 9 publications

References 0 publications

Epistaxis and Its Associated Factors Among Precollege Students in Southern Ethiopia

Epistaxis and Its Associated Factors Among Precollege Students in Southern Ethiopia

To check the abundance of specific ABO blood groups and its coordination with bleeding time and clotting time among individuals of different ethnicity in Quetta, Balochistan

Optimasi Hidrolisis Mikrobiologi serta Bioaktivitas Antibakteri, Antioksidan, dan Antikoagulan Hidrolisat Ulva lactuca

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