Distribution of Coagulase-Negative Staphylococci and Antibiotic Resistance

Abstract

Coagulase-negative staphylococci (CoNS) are a typical group of microorganisms, and the recent advances in laboratory technology and medicine has dramatically modified their significance in medical practice. CoNS, which were previously classified as normal bacterial flora, have recently been reported to be associated with serious infectious diseases, such as surgical wound infection or periprosthetic joint infection. Representative CoNS include Staphylococcus epidermidis, S. haemolyticus, and S. saprophyticus, which are known to cause serious problems in biomaterial-based and prosthetic device infections, as well as to cause simple urinary tract infections in sexually active women. Over the last decade, the clinical isolation rate of CoNS has been increasing, and antibiotic resistance has also been occurring. This review aimed to investigate the incidence of CoNS infection and to use the results as basic data for the management of CoNS, with a focus on the isolation rate and antibiotic resistance in clinical surgery.

Antibiotic sensitivity pattern of coagulase negative staphylococci in a tertiary care hospital of Southern Rajasthan

“…1,2 In recent years, CoNS have emerged as one of important source of hospital acquired infections. 3,4 They can lead to infections in patients who are immunocompromised and can spread through contaminated devices like intravenous catheters, urinary catheters and orthopaedic prosthesis. 2,5 The management of these infections is difficult due to widespread use of antibiotics and development of multidrug resistance.…”

Antibiotic resistance patterns of methicillin-resistant coagulase negative staphylococci isolated from blood cultures at a university hospital in Turkey

“…Adhesion of CoNS causes severe infections in various prosthetic and peritoneal dialysis catheters, orthopedic implants, prosthetic heart valves, supra-pubic catheters, joint prostheses, cerebrospinal shunts, invasive vascular catheters and urinary catheters. Recently, the rapid resistance of bacteria to various antibiotics has become a serious problem for clinicians (García-Vázquez et al, 2013;Karakullukçu et al, 2017;Park et al, 2021). In this regard, up-to-date resistance information is needed for bacteria responsible for emerging infections that threaten human health, like infections caused by CoNS.…”